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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPR
All Species:
46.36
Human Site:
Y170
Identified Species:
78.46
UniProt:
P35270
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35270
NP_003115.1
261
28048
Y170
P
F
K
G
W
A
L
Y
C
A
G
K
A
A
R
Chimpanzee
Pan troglodytes
XP_525784
261
27897
Y170
P
F
K
G
W
A
L
Y
C
A
G
K
A
A
R
Rhesus Macaque
Macaca mulatta
XP_001103332
261
28016
Y170
P
F
K
G
W
A
L
Y
C
A
G
K
A
A
R
Dog
Lupus familis
XP_540234
267
28592
Y176
P
F
K
G
W
G
L
Y
C
A
G
K
A
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64105
261
27865
Y171
P
Y
K
G
W
G
L
Y
C
A
G
K
A
A
R
Rat
Rattus norvegicus
P18297
262
28110
Y171
P
F
K
G
W
G
L
Y
C
A
G
K
A
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520473
236
25629
Y131
P
Y
K
S
W
G
L
Y
C
A
G
K
A
A
R
Chicken
Gallus gallus
Q8JIS3
246
26149
Y151
A
L
R
D
H
A
V
Y
C
S
T
K
S
A
L
Frog
Xenopus laevis
Q7ZY31
263
28687
Y173
P
Y
K
S
W
V
L
Y
C
S
G
K
A
A
R
Zebra Danio
Brachydanio rerio
NP_001019601
261
28523
Y170
P
F
P
T
W
V
Q
Y
C
S
G
K
A
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624245
354
39811
Y262
P
E
K
S
M
A
Y
Y
C
S
G
K
A
A
R
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
Y156
P
L
D
N
H
T
V
Y
C
A
S
K
A
A
L
Sea Urchin
Strong. purpuratus
XP_783056
275
30198
Y175
P
M
K
T
C
G
L
Y
C
M
V
K
A
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40579
254
27462
Y150
Y
F
S
S
W
G
A
Y
G
S
S
K
A
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
96.9
80.9
N.A.
74.3
74.4
N.A.
46.3
26.4
55.5
52.4
N.A.
N.A.
25.4
26
39.6
Protein Similarity:
100
98
99.6
89.1
N.A.
86.5
88.1
N.A.
58.6
44.8
69.9
74.3
N.A.
N.A.
41.5
46.3
58.5
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
80
33.3
73.3
66.6
N.A.
N.A.
66.6
46.6
60
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
60
86.6
73.3
N.A.
N.A.
73.3
53.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
36
8
0
0
58
0
0
93
100
0
% A
% Cys:
0
0
0
0
8
0
0
0
93
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
43
0
43
0
0
8
0
72
0
0
0
0
% G
% His:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
72
0
0
0
0
0
0
0
0
100
0
0
0
% K
% Leu:
0
15
0
0
0
0
65
0
0
0
0
0
0
0
22
% L
% Met:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
86
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
79
% R
% Ser:
0
0
8
29
0
0
0
0
0
36
15
0
8
0
0
% S
% Thr:
0
0
0
15
0
8
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
15
15
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
22
0
0
0
0
8
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _