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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1A
All Species:
26.97
Human Site:
S220
Identified Species:
65.93
UniProt:
P35348
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35348
NP_000671.2
466
51487
S220
R
E
S
R
G
L
K
S
G
L
K
T
D
K
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001108205
466
51398
S220
R
E
S
R
G
L
K
S
G
L
K
T
D
K
S
Dog
Lupus familis
XP_534567
466
51508
S220
R
E
S
R
G
L
K
S
G
L
K
T
D
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P97718
466
51744
S220
R
E
S
R
G
L
K
S
G
L
K
T
D
K
S
Rat
Rattus norvegicus
P43140
466
51579
S220
R
E
S
R
G
L
K
S
G
L
K
T
D
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520086
428
47465
Y199
F
S
A
L
G
S
F
Y
V
P
L
A
I
I
L
Chicken
Gallus gallus
XP_425762
467
51190
S220
R
E
N
K
G
L
R
S
G
L
K
M
E
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338938
478
52644
S227
R
E
T
R
G
L
I
S
G
Q
K
T
E
K
S
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
D194
A
E
D
R
A
N
P
D
A
C
I
I
S
Q
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
G235
V
E
Y
K
S
R
H
G
G
K
S
H
G
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.2
92.9
N.A.
91.8
92.6
N.A.
56.6
77
N.A.
58.7
25.1
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
N.A.
98.9
96.3
N.A.
95.4
96.1
N.A.
66.9
86.7
N.A.
73.6
44.8
N.A.
N.A.
N.A.
49.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
66.6
N.A.
73.3
13.3
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
86.6
20
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
0
0
0
10
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
10
0
0
0
0
50
0
10
% D
% Glu:
0
90
0
0
0
0
0
0
0
0
0
0
20
0
0
% E
% Phe:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
80
0
0
10
80
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
10
10
10
10
0
% I
% Lys:
0
0
0
20
0
0
50
0
0
10
70
0
0
70
0
% K
% Leu:
0
0
0
10
0
70
0
0
0
60
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
70
0
0
70
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
50
0
10
10
0
70
0
0
10
0
10
10
70
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
60
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _