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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1A
All Species:
19.09
Human Site:
S407
Identified Species:
46.67
UniProt:
P35348
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35348
NP_000671.2
466
51487
S407
F
S
S
M
P
R
G
S
A
R
I
T
V
S
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001108205
466
51398
S407
F
S
S
M
P
R
G
S
A
R
I
T
V
S
K
Dog
Lupus familis
XP_534567
466
51508
S407
F
S
S
M
P
R
E
S
A
R
I
T
V
S
K
Cat
Felis silvestris
Mouse
Mus musculus
P97718
466
51744
S407
F
S
S
M
P
Q
G
S
A
R
I
T
M
P
K
Rat
Rattus norvegicus
P43140
466
51579
S407
F
S
S
M
P
Q
G
S
A
R
I
T
V
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520086
428
47465
M370
I
P
L
F
F
W
L
M
G
A
Y
I
C
H
L
Chicken
Gallus gallus
XP_425762
467
51190
P408
F
S
A
V
Q
S
V
P
T
K
S
A
I
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338938
478
52644
T419
R
T
S
S
V
G
T
T
G
V
S
T
G
V
S
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
V365
C
W
L
P
F
F
I
V
A
L
V
L
P
F
C
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
S500
H
P
E
H
E
E
S
S
F
H
E
R
G
H
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.2
92.9
N.A.
91.8
92.6
N.A.
56.6
77
N.A.
58.7
25.1
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
N.A.
98.9
96.3
N.A.
95.4
96.1
N.A.
66.9
86.7
N.A.
73.6
44.8
N.A.
N.A.
N.A.
49.8
P-Site Identity:
100
N.A.
100
93.3
N.A.
80
86.6
N.A.
0
20
N.A.
13.3
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
0
46.6
N.A.
26.6
13.3
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
60
10
0
10
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
10
10
0
0
0
10
0
0
0
0
% E
% Phe:
60
0
0
10
20
10
0
0
10
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
40
0
20
0
0
0
20
0
0
% G
% His:
10
0
0
10
0
0
0
0
0
10
0
0
0
20
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
50
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
60
% K
% Leu:
0
0
20
0
0
0
10
0
0
10
0
10
0
0
10
% L
% Met:
0
0
0
50
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
20
0
10
50
0
0
10
0
0
0
0
10
30
0
% P
% Gln:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
30
0
0
0
50
0
10
0
0
10
% R
% Ser:
0
60
60
10
0
10
10
60
0
0
20
0
0
30
10
% S
% Thr:
0
10
0
0
0
0
10
10
10
0
0
60
0
0
0
% T
% Val:
0
0
0
10
10
0
10
10
0
10
10
0
40
10
0
% V
% Trp:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _