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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA1A
All Species:
12.73
Human Site:
S442
Identified Species:
31.11
UniProt:
P35348
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35348
NP_000671.2
466
51487
S442
C
V
G
P
S
T
P
S
L
D
K
N
H
Q
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
NP_001108205
466
51398
S442
C
V
G
P
S
T
P
S
L
D
K
N
H
Q
V
Dog
Lupus familis
XP_534567
466
51508
S442
C
M
G
P
S
T
P
S
H
G
E
N
H
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
P97718
466
51744
R442
C
V
G
S
S
T
P
R
P
E
E
N
H
Q
V
Rat
Rattus norvegicus
P43140
466
51579
R442
C
V
G
S
S
A
P
R
P
E
E
N
H
Q
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520086
428
47465
A405
P
I
I
Y
S
A
L
A
L
L
F
K
A
C
L
Chicken
Gallus gallus
XP_425762
467
51190
T443
C
A
G
T
S
G
N
T
V
H
E
N
C
K
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001338938
478
52644
E454
R
A
D
S
P
Q
P
E
P
P
A
Q
N
S
L
Tiger Blowfish
Takifugu rubipres
O42385
423
46982
I400
N
S
L
L
N
P
I
I
Y
A
Y
F
N
K
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203873
574
63580
S535
S
K
N
P
E
S
S
S
A
S
E
G
I
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.2
92.9
N.A.
91.8
92.6
N.A.
56.6
77
N.A.
58.7
25.1
N.A.
N.A.
N.A.
33.4
Protein Similarity:
100
N.A.
98.9
96.3
N.A.
95.4
96.1
N.A.
66.9
86.7
N.A.
73.6
44.8
N.A.
N.A.
N.A.
49.8
P-Site Identity:
100
N.A.
100
66.6
N.A.
66.6
60
N.A.
13.3
33.3
N.A.
6.6
0
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
N.A.
100
86.6
N.A.
80
73.3
N.A.
33.3
60
N.A.
20
20
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
20
0
10
10
10
10
0
10
0
0
% A
% Cys:
60
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
20
0
0
0
0
10
% D
% Glu:
0
0
0
0
10
0
0
10
0
20
50
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
0
60
0
0
10
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
10
0
0
50
0
0
% H
% Ile:
0
10
10
0
0
0
10
10
0
0
0
0
10
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
20
10
0
20
0
% K
% Leu:
0
0
10
10
0
0
10
0
30
10
0
0
0
0
20
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
10
0
10
0
0
0
0
60
20
0
0
% N
% Pro:
10
0
0
40
10
10
60
0
30
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
10
0
60
0
% Q
% Arg:
10
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
30
70
10
10
40
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
10
0
40
0
10
0
0
0
0
0
0
0
% T
% Val:
0
40
0
0
0
0
0
0
10
0
0
0
0
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _