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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
35.15
Human Site:
T60
Identified Species:
59.49
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
T60
R
S
E
R
K
L
H
T
V
G
N
L
Y
I
V
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
T60
R
S
E
R
K
L
H
T
V
G
N
L
Y
I
V
Rhesus Macaque
Macaca mulatta
P56490
532
60122
T63
K
V
N
S
Q
L
K
T
V
N
N
Y
Y
L
L
Dog
Lupus familis
XP_541769
536
61594
T109
R
S
E
R
K
L
H
T
V
G
N
L
Y
I
V
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
T60
R
S
E
R
K
L
H
T
V
G
N
L
Y
I
V
Rat
Rattus norvegicus
P31390
486
55674
T60
H
S
E
R
K
L
H
T
V
G
N
L
Y
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
S60
N
L
Y
I
V
S
L
S
V
A
D
L
I
V
G
Chicken
Gallus gallus
P30372
466
51547
N61
N
R
H
L
Q
T
V
N
N
Y
F
L
F
S
L
Frog
Xenopus laevis
P30544
484
54107
T66
K
V
N
R
Q
L
Q
T
V
N
N
Y
F
L
F
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
T84
R
K
E
R
T
L
H
T
V
G
N
L
Y
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
T109
C
R
E
R
S
L
Q
T
V
T
N
Y
F
I
V
Honey Bee
Apis mellifera
XP_395477
546
60788
Q115
I
V
D
R
A
I
R
Q
P
S
N
Y
F
I
A
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
N75
C
T
K
K
Y
L
R
N
P
T
G
Y
L
I
I
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
T93
R
T
D
R
R
L
R
T
V
S
N
Y
F
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
33.3
100
N.A.
100
93.3
N.A.
13.3
6.6
33.3
86.6
N.A.
53.3
20
13.3
46.6
P-Site Similarity:
100
100
60
100
N.A.
100
93.3
N.A.
33.3
26.6
60
86.6
N.A.
60
40
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% A
% Cys:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
36
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
43
8
0
0
0
8
% G
% His:
8
0
8
0
0
0
43
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
0
0
0
0
0
0
8
72
8
% I
% Lys:
15
8
8
8
36
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
0
79
8
0
0
0
0
58
8
15
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
15
0
0
0
0
15
8
15
79
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
22
0
15
8
0
0
0
0
0
0
0
% Q
% Arg:
43
15
0
72
8
0
22
0
0
0
0
0
0
0
0
% R
% Ser:
0
36
0
8
8
8
0
8
0
15
0
0
0
8
0
% S
% Thr:
0
15
0
0
8
8
0
72
0
15
0
0
0
0
0
% T
% Val:
0
22
0
0
8
0
8
0
79
0
0
0
0
8
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
8
0
0
0
0
8
0
43
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _