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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HRH1
All Species:
21.21
Human Site:
Y386
Identified Species:
35.9
UniProt:
P35367
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35367
NP_000852.1
487
55784
Y386
G
S
N
T
G
L
D
Y
I
K
F
T
W
K
R
Chimpanzee
Pan troglodytes
Q9N2B2
487
55605
Y386
G
S
N
T
G
L
D
Y
I
K
F
T
W
K
R
Rhesus Macaque
Macaca mulatta
P56490
532
60122
A410
M
P
C
S
F
P
V
A
K
E
P
S
T
K
G
Dog
Lupus familis
XP_541769
536
61594
Y435
E
S
S
T
G
L
D
Y
I
K
F
T
W
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P70174
488
55663
Y387
R
S
N
S
G
L
D
Y
I
K
V
T
W
K
R
Rat
Rattus norvegicus
P31390
486
55674
Y385
G
S
N
S
G
L
D
Y
I
K
I
T
W
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505379
489
54959
Y388
G
P
S
G
L
G
G
Y
L
K
Y
T
W
K
R
Chicken
Gallus gallus
P30372
466
51547
P377
K
Q
P
A
K
K
K
P
P
P
S
R
E
K
K
Frog
Xenopus laevis
P30544
484
54107
R394
R
N
Q
V
R
K
K
R
Q
M
A
A
R
E
K
Zebra Danio
Brachydanio rerio
NP_001036196
534
61056
P433
L
D
A
S
I
A
L
P
A
K
Q
S
W
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IS44
506
56459
R426
K
S
S
A
K
K
E
R
K
A
T
K
T
L
A
Honey Bee
Apis mellifera
XP_395477
546
60788
P442
N
V
A
S
Q
T
S
P
T
T
K
T
Q
R
R
Nematode Worm
Caenorhab. elegans
Q18775
517
58629
Y400
K
S
R
Q
M
M
R
Y
V
H
E
Q
R
A
A
Sea Urchin
Strong. purpuratus
NP_001012721
677
76342
A548
Q
V
K
N
G
G
V
A
G
R
F
S
F
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
27
78.5
N.A.
78
78.8
N.A.
60.1
27.3
27.7
41.3
N.A.
28.6
28.3
26.8
29.2
Protein Similarity:
100
99.1
44.7
83.4
N.A.
84.6
85.6
N.A.
70.7
47.2
44.5
57.1
N.A.
48.8
43
46.8
49
P-Site Identity:
100
100
6.6
86.6
N.A.
80
86.6
N.A.
46.6
6.6
0
13.3
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
100
26.6
93.3
N.A.
86.6
93.3
N.A.
66.6
13.3
20
40
N.A.
20
26.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
15
0
8
0
15
8
8
8
8
0
15
15
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
36
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
8
0
0
8
8
0
8
8
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
29
0
8
0
0
% F
% Gly:
29
0
0
8
43
15
8
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
36
0
8
0
0
0
0
% I
% Lys:
22
0
8
0
15
22
15
0
15
50
8
8
0
58
22
% K
% Leu:
8
0
0
0
8
36
8
0
8
0
0
0
0
8
0
% L
% Met:
8
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% M
% Asn:
8
8
29
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
15
8
0
0
8
0
22
8
8
8
0
0
0
0
% P
% Gln:
8
8
8
8
8
0
0
0
8
0
8
8
8
8
0
% Q
% Arg:
15
0
8
0
8
0
8
15
0
8
0
8
15
8
58
% R
% Ser:
0
50
22
36
0
0
8
0
0
0
8
22
0
0
0
% S
% Thr:
0
0
0
22
0
8
0
0
8
8
8
50
15
0
0
% T
% Val:
0
15
0
8
0
0
15
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _