KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPRM1
All Species:
22.73
Human Site:
S377
Identified Species:
62.5
UniProt:
P35372
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35372
NP_000905.3
400
44779
S377
Q
N
T
R
D
H
P
S
T
A
N
T
V
D
R
Chimpanzee
Pan troglodytes
Q5IS39
401
44883
S378
Q
N
T
R
D
H
P
S
T
A
N
T
V
D
R
Rhesus Macaque
Macaca mulatta
Q9MYW9
400
44791
S377
Q
N
T
R
D
H
P
S
T
A
N
T
V
D
R
Dog
Lupus familis
XP_541158
401
44921
S378
Q
N
T
R
D
H
P
S
T
A
N
T
V
D
R
Cat
Felis silvestris
Mouse
Mus musculus
P42866
398
44402
S375
Q
N
T
R
E
H
P
S
T
A
N
T
V
D
R
Rat
Rattus norvegicus
P33535
398
44475
S375
Q
N
T
R
E
H
P
S
T
A
N
T
V
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510524
312
35765
R290
I
E
Q
Q
N
S
T
R
I
R
Q
N
T
R
D
Chicken
Gallus gallus
XP_427506
366
40984
R344
V
E
Q
N
S
F
S
R
A
R
N
T
T
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571782
384
43137
R362
L
D
L
Q
N
S
T
R
S
R
N
P
Q
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98
96
N.A.
94
94
N.A.
73
62
N.A.
72.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
99
97.5
N.A.
96.2
96.5
N.A.
75
71.7
N.A.
79
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
12
67
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
45
0
0
0
0
0
0
0
0
67
23
% D
% Glu:
0
23
0
0
23
0
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
67
0
12
23
0
0
0
0
0
89
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
67
0
0
0
0
12
0
0
0
% P
% Gln:
67
0
23
23
0
0
0
0
0
0
12
0
12
0
0
% Q
% Arg:
0
0
0
67
0
0
0
34
0
34
0
0
0
34
67
% R
% Ser:
0
0
0
0
12
23
12
67
12
0
0
0
0
0
0
% S
% Thr:
0
0
67
0
0
0
23
0
67
0
0
78
23
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _