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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTGER4
All Species:
22.42
Human Site:
S443
Identified Species:
54.81
UniProt:
P35408
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35408
NP_000949.1
488
53119
S443
I
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Chimpanzee
Pan troglodytes
Q95KZ0
490
53285
S445
I
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001085257
490
53448
S445
I
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Dog
Lupus familis
XP_541544
384
40823
G340
R
P
P
A
A
L
G
G
T
E
G
S
W
V
P
Cat
Felis silvestris
Mouse
Mus musculus
P32240
513
56140
S468
I
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Rat
Rattus norvegicus
P43114
488
53347
S443
I
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506946
563
60666
D505
D
T
L
T
E
E
T
D
L
K
N
V
T
T
T
Chicken
Gallus gallus
NP_001074972
475
51995
S430
S
S
E
T
S
D
S
S
Q
G
Q
D
S
E
S
Frog
Xenopus laevis
NP_001084446
371
41878
K327
C
Q
K
P
F
K
I
K
E
I
A
K
S
P
S
Zebra Danio
Brachydanio rerio
NP_001034718
403
44336
N359
S
T
S
Q
T
S
L
N
L
A
K
A
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
29.9
N.A.
83.6
88.3
N.A.
49.9
74.5
28.4
57.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.3
44.6
N.A.
88.5
93
N.A.
61.8
82.7
45.7
67.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
6.6
93.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
40
93.3
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
10
10
10
0
10
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
60
0
10
0
0
0
60
0
0
0
% D
% Glu:
0
0
60
0
10
10
0
0
10
10
0
0
0
60
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
10
0
60
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
10
0
10
10
10
0
0
0
% K
% Leu:
0
0
10
0
0
10
10
0
20
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% N
% Pro:
0
10
10
10
0
0
0
0
0
0
0
0
10
10
10
% P
% Gln:
0
10
0
10
0
0
0
0
60
0
60
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
60
10
0
60
10
60
60
0
0
0
10
70
0
70
% S
% Thr:
0
20
0
70
10
0
10
0
10
0
0
0
10
10
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _