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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THBS4
All Species:
28.48
Human Site:
Y470
Identified Species:
78.33
UniProt:
P35443
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35443
NP_003239.2
961
105869
Y470
K
D
V
D
I
D
S
Y
P
D
E
E
L
P
C
Chimpanzee
Pan troglodytes
XP_001154764
956
104153
Y464
T
D
T
D
I
D
G
Y
P
D
Q
A
L
P
C
Rhesus Macaque
Macaca mulatta
XP_001109898
961
105916
Y470
K
D
V
D
I
D
S
Y
P
D
E
E
L
P
C
Dog
Lupus familis
XP_546047
964
106106
Y473
K
D
V
D
I
D
S
Y
P
D
E
E
L
P
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T2
963
106348
Y472
K
D
V
D
I
D
S
Y
P
D
E
E
L
P
C
Rat
Rattus norvegicus
P49744
980
108195
Y489
K
D
V
D
I
D
S
Y
P
D
E
E
L
P
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P35440
1178
131798
W706
E
D
S
D
L
D
G
W
P
N
N
N
L
V
C
Frog
Xenopus laevis
Q06441
955
104900
Y467
K
D
T
D
I
D
G
Y
P
D
E
A
L
P
C
Zebra Danio
Brachydanio rerio
Q8JGW0
949
103972
Y459
K
D
T
D
I
D
G
Y
P
D
E
R
L
R
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.4
98.2
91.1
N.A.
92.3
90.9
N.A.
N.A.
37.9
73.3
69.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.6
99.1
94.6
N.A.
96.1
94.9
N.A.
N.A.
50.5
84
80.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
N.A.
40
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
66.6
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
100
0
100
0
100
0
0
0
89
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
78
56
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
89
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
78
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
0
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
12
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
100
0
0
0
0
78
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% R
% Ser:
0
0
12
0
0
0
56
0
0
0
0
0
0
0
0
% S
% Thr:
12
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
56
0
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _