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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDUA
All Species:
7.88
Human Site:
S443
Identified Species:
21.67
UniProt:
P35475
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35475
NP_000194.2
653
72670
S443
A
A
V
L
I
Y
A
S
D
D
T
R
A
H
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48441
634
71162
S433
T
T
V
L
I
Y
T
S
D
D
T
H
A
H
P
Rat
Rattus norvegicus
NP_001165555
643
72397
S442
T
T
V
L
I
Y
T
S
D
D
T
H
I
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514102
730
83333
A530
Q
A
T
V
L
V
Y
A
S
D
D
N
R
T
S
Chicken
Gallus gallus
NP_001026604
630
71545
S431
Q
A
T
L
L
M
Y
S
S
E
D
N
R
T
S
Frog
Xenopus laevis
NP_001087031
630
72098
A430
Q
S
T
I
L
C
Y
A
S
D
D
N
K
T
S
Zebra Danio
Brachydanio rerio
XP_001923689
645
73707
N446
Q
S
S
V
L
I
Y
N
S
R
D
N
Q
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609489
636
72281
E432
A
T
I
F
L
S
P
E
E
A
G
P
K
M
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796813
596
67141
A400
S
I
L
I
H
N
S
A
D
T
D
N
V
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
76.8
76.8
N.A.
56.4
57.4
52.5
53.1
N.A.
29.2
N.A.
N.A.
42.1
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
83.4
84.6
N.A.
68.3
72.5
70.2
70.7
N.A.
47.1
N.A.
N.A.
58.3
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
73.3
66.6
N.A.
13.3
20
6.6
0
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
73.3
66.6
N.A.
33.3
33.3
33.3
26.6
N.A.
26.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
34
0
0
0
0
12
34
0
12
0
0
23
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
45
56
56
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
12
12
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% G
% His:
0
0
0
0
12
0
0
0
0
0
0
23
0
34
0
% H
% Ile:
0
12
12
23
34
12
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% K
% Leu:
0
0
12
45
56
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
12
0
12
0
0
0
56
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
34
% P
% Gln:
45
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
12
23
0
0
% R
% Ser:
12
23
12
0
0
12
12
45
45
0
0
0
0
0
45
% S
% Thr:
23
34
34
0
0
0
23
0
0
12
34
0
0
56
12
% T
% Val:
0
0
34
23
0
12
0
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
34
45
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _