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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDUA
All Species:
13.94
Human Site:
Y64
Identified Species:
38.33
UniProt:
P35475
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35475
NP_000194.2
653
72670
Y64
P
H
S
Q
A
D
Q
Y
V
L
S
W
D
Q
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P48441
634
71162
Y54
P
H
D
Q
A
D
Q
Y
D
L
S
W
D
Q
Q
Rat
Rattus norvegicus
NP_001165555
643
72397
Y63
P
H
D
Q
A
D
Q
Y
D
L
S
W
D
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514102
730
83333
F151
P
H
N
K
S
E
L
F
D
L
S
K
D
Q
R
Chicken
Gallus gallus
NP_001026604
630
71545
F52
P
H
S
S
A
D
L
F
D
L
S
K
D
Q
E
Frog
Xenopus laevis
NP_001087031
630
72098
Y55
P
H
D
K
S
E
A
Y
F
L
G
K
D
Q
Q
Zebra Danio
Brachydanio rerio
XP_001923689
645
73707
Y65
P
H
T
D
A
H
L
Y
D
L
S
P
D
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609489
636
72281
A51
D
H
E
G
I
S
A
A
L
G
D
P
A
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796813
596
67141
K38
S
V
P
R
D
G
I
K
Q
V
R
I
H
W
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
76.8
76.8
N.A.
56.4
57.4
52.5
53.1
N.A.
29.2
N.A.
N.A.
42.1
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
83.4
84.6
N.A.
68.3
72.5
70.2
70.7
N.A.
47.1
N.A.
N.A.
58.3
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
86.6
86.6
N.A.
40
60
46.6
60
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
86.6
86.6
N.A.
80
73.3
66.6
66.6
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
56
0
23
12
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
34
12
12
45
0
0
56
0
12
0
78
0
0
% D
% Glu:
0
0
12
0
0
23
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
23
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
12
0
0
0
12
12
0
0
0
0
% G
% His:
0
89
0
0
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
12
0
12
0
0
0
0
12
0
0
0
% I
% Lys:
0
0
0
23
0
0
0
12
0
0
0
34
0
0
0
% K
% Leu:
0
0
0
0
0
0
34
0
12
78
0
0
0
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
78
0
12
0
0
0
0
0
0
0
0
23
0
0
0
% P
% Gln:
0
0
0
34
0
0
34
0
12
0
0
0
0
78
56
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
23
% R
% Ser:
12
0
23
12
23
12
0
0
0
0
67
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
12
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
34
0
12
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _