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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UGT1A5 All Species: 13.64
Human Site: Y294 Identified Species: 75
UniProt: P35504 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35504 NP_061951.1 534 60071 Y294 L S Q E F E A Y I N A S G E H
Chimpanzee Pan troglodytes XP_001150961 534 60301 Y294 L S Q E F E A Y I N A S G E H
Rhesus Macaque Macaca mulatta Q9GLD9 529 60840 F295 L P K E M E E F V Q S S G E N
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P70691 533 60267 Y293 L S Q E F E A Y V N A S G E H
Rat Rattus norvegicus P20720 533 60027 Y293 L S Q E F E A Y V N A S G E H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.9 44.3 N.A. N.A. 74.1 75 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 62.5 N.A. N.A. 84.4 84.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 40 N.A. N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 80 0 0 0 80 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 100 20 0 0 0 0 0 0 100 0 % E
% Phe: 0 0 0 0 80 0 0 20 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % H
% Ile: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % I
% Lys: 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 20 % N
% Pro: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 80 0 0 0 0 0 0 20 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 80 0 0 0 0 0 0 0 0 20 100 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _