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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN1
All Species:
20.91
Human Site:
S707
Identified Species:
38.33
UniProt:
P35523
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35523
NP_000074.2
988
108756
S707
A
P
P
G
R
P
E
S
F
A
F
V
D
E
D
Chimpanzee
Pan troglodytes
XP_527935
988
108838
S707
A
P
P
G
R
P
E
S
F
A
F
V
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001092282
736
80740
P478
S
E
L
P
P
S
L
P
L
H
P
S
T
T
A
Dog
Lupus familis
XP_859634
871
95882
S611
A
L
V
E
S
P
E
S
M
I
L
L
G
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q64347
994
109776
S704
H
P
G
G
R
P
E
S
F
A
F
V
D
E
D
Rat
Rattus norvegicus
P35524
994
110055
S704
H
P
G
G
R
P
E
S
F
A
F
V
D
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
F611
G
W
N
Q
L
S
K
F
T
I
F
V
E
D
I
Chicken
Gallus gallus
XP_425521
996
111070
S712
L
P
K
L
N
R
E
S
F
V
Y
V
D
E
D
Frog
Xenopus laevis
Q9W701
689
76782
V431
P
A
G
Y
F
M
P
V
F
V
F
G
A
A
I
Zebra Danio
Brachydanio rerio
XP_695866
879
96751
S615
V
S
E
G
S
W
E
S
F
V
F
V
D
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
T848
A
I
F
K
K
S
T
T
L
Q
D
V
Q
P
D
Honey Bee
Apis mellifera
XP_392015
919
102193
R654
E
R
T
R
R
P
S
R
F
E
V
I
P
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
V521
T
N
L
T
L
T
V
V
V
I
M
F
E
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
49.7
N.A.
87.4
87.8
N.A.
63.8
65.8
32.4
56.3
N.A.
34.9
36
N.A.
N.A.
Protein Similarity:
100
99.8
72.9
64
N.A.
91.4
91.9
N.A.
71.3
77.1
47.4
68.3
N.A.
51.9
52.4
N.A.
N.A.
P-Site Identity:
100
100
0
26.6
N.A.
86.6
86.6
N.A.
13.3
53.3
13.3
53.3
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
100
6.6
33.3
N.A.
86.6
86.6
N.A.
33.3
60
13.3
60
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
8
0
0
0
0
0
0
0
31
0
0
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
47
8
47
% D
% Glu:
8
8
8
8
0
0
54
0
0
8
0
0
16
47
8
% E
% Phe:
0
0
8
0
8
0
0
8
62
0
54
8
0
0
0
% F
% Gly:
8
0
24
39
0
0
0
0
0
0
0
8
8
0
0
% G
% His:
16
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
24
0
8
0
0
24
% I
% Lys:
0
0
8
8
8
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
16
8
16
0
8
0
16
0
8
8
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% M
% Asn:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
39
16
8
8
47
8
8
0
0
8
0
8
8
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
0
8
39
8
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
0
16
24
8
54
0
0
0
8
0
8
0
% S
% Thr:
8
0
8
8
0
8
8
8
8
0
0
0
8
8
8
% T
% Val:
8
0
8
0
0
0
8
16
8
24
8
62
0
0
0
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _