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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN1
All Species:
11.52
Human Site:
S728
Identified Species:
21.11
UniProt:
P35523
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35523
NP_000074.2
988
108756
S728
G
K
S
E
L
P
P
S
L
A
L
H
P
S
T
Chimpanzee
Pan troglodytes
XP_527935
988
108838
S728
G
K
S
E
L
P
P
S
L
P
L
H
P
S
T
Rhesus Macaque
Macaca mulatta
XP_001092282
736
80740
H499
P
N
G
P
L
P
G
H
K
Q
Q
P
E
A
P
Dog
Lupus familis
XP_859634
871
95882
S632
A
L
L
G
A
Q
L
S
P
A
R
R
R
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q64347
994
109776
T725
R
K
M
E
L
P
L
T
P
A
P
P
P
P
S
Rat
Rattus norvegicus
P35524
994
110055
T725
R
K
T
E
L
P
Q
T
P
T
P
P
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
Y632
F
V
S
A
S
C
T
Y
R
D
L
Q
A
L
L
Chicken
Gallus gallus
XP_425521
996
111070
P733
A
E
P
Q
P
P
S
P
S
P
S
H
P
E
E
Frog
Xenopus laevis
Q9W701
689
76782
E452
T
V
A
L
L
Y
P
E
G
I
A
A
D
G
I
Zebra Danio
Brachydanio rerio
XP_695866
879
96751
E636
D
K
G
N
R
V
S
E
E
C
N
G
P
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
E869
S
P
A
A
S
N
H
E
V
E
V
P
R
T
P
Honey Bee
Apis mellifera
XP_392015
919
102193
T675
R
Q
S
A
N
D
L
T
M
S
P
S
N
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
A542
I
P
L
M
I
V
V
A
I
T
R
I
I
L
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
49.7
N.A.
87.4
87.8
N.A.
63.8
65.8
32.4
56.3
N.A.
34.9
36
N.A.
N.A.
Protein Similarity:
100
99.8
72.9
64
N.A.
91.4
91.9
N.A.
71.3
77.1
47.4
68.3
N.A.
51.9
52.4
N.A.
N.A.
P-Site Identity:
100
93.3
13.3
13.3
N.A.
40
33.3
N.A.
13.3
20
13.3
13.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
20
13.3
N.A.
53.3
46.6
N.A.
13.3
33.3
20
13.3
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
24
8
0
0
8
0
24
8
8
8
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% D
% Glu:
0
8
0
31
0
0
0
24
8
8
0
0
8
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
16
8
0
0
8
0
8
0
0
8
0
16
8
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
24
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
8
0
8
8
0
8
% I
% Lys:
0
39
0
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
16
8
47
0
24
0
16
0
24
0
0
16
8
% L
% Met:
0
0
8
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
8
8
0
0
0
0
8
0
8
0
0
% N
% Pro:
8
16
8
8
8
47
24
8
24
16
24
31
47
16
24
% P
% Gln:
0
8
0
8
0
8
8
0
0
8
8
8
0
8
0
% Q
% Arg:
24
0
0
0
8
0
0
0
8
0
16
8
16
0
0
% R
% Ser:
8
0
31
0
16
0
16
24
8
8
8
8
0
16
16
% S
% Thr:
8
0
8
0
0
0
8
24
0
16
0
0
0
8
16
% T
% Val:
0
16
0
0
0
16
8
0
8
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _