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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN1
All Species:
20
Human Site:
Y261
Identified Species:
36.67
UniProt:
P35523
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35523
NP_000074.2
988
108756
Y261
C
G
V
Y
E
Q
P
Y
Y
Y
S
D
I
L
T
Chimpanzee
Pan troglodytes
XP_527935
988
108838
Y261
C
G
V
Y
E
Q
P
Y
Y
Y
S
D
I
L
T
Rhesus Macaque
Macaca mulatta
XP_001092282
736
80740
H117
G
A
V
F
V
Y
L
H
R
Q
V
M
L
G
V
Dog
Lupus familis
XP_859634
871
95882
C242
C
A
V
G
V
G
C
C
F
A
A
P
I
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64347
994
109776
Y261
S
G
V
Y
E
Q
P
Y
Y
Y
T
D
I
L
T
Rat
Rattus norvegicus
P35524
994
110055
Y261
S
G
V
Y
E
Q
P
Y
Y
Y
T
D
I
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
E237
S
G
I
P
V
G
K
E
P
L
A
C
L
S
P
Chicken
Gallus gallus
XP_425521
996
111070
Y269
C
G
V
Y
E
Q
P
Y
Y
Y
T
D
V
L
T
Frog
Xenopus laevis
Q9W701
689
76782
F70
L
I
S
F
T
M
D
F
T
V
S
K
M
L
N
Zebra Danio
Brachydanio rerio
XP_695866
879
96751
I239
A
A
T
F
S
A
F
I
F
R
V
L
S
V
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
S315
Q
G
I
Y
E
N
E
S
R
N
S
E
M
L
A
Honey Bee
Apis mellifera
XP_392015
919
102193
L236
A
A
P
I
G
G
V
L
F
S
I
E
V
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
I160
G
H
V
S
P
F
I
I
F
M
L
L
S
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
49.7
N.A.
87.4
87.8
N.A.
63.8
65.8
32.4
56.3
N.A.
34.9
36
N.A.
N.A.
Protein Similarity:
100
99.8
72.9
64
N.A.
91.4
91.9
N.A.
71.3
77.1
47.4
68.3
N.A.
51.9
52.4
N.A.
N.A.
P-Site Identity:
100
100
6.6
20
N.A.
86.6
86.6
N.A.
6.6
86.6
13.3
0
N.A.
33.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
26.6
33.3
N.A.
93.3
93.3
N.A.
26.6
100
33.3
20
N.A.
53.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
31
0
0
0
8
0
0
0
8
16
0
0
0
8
% A
% Cys:
31
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
39
0
0
0
% D
% Glu:
0
0
0
0
47
0
8
8
0
0
0
16
0
0
0
% E
% Phe:
0
0
0
24
0
8
8
8
31
0
0
0
0
0
0
% F
% Gly:
16
54
0
8
8
24
0
0
0
0
0
0
0
16
8
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
8
0
0
8
16
0
0
8
0
39
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% K
% Leu:
8
0
0
0
0
0
8
8
0
8
8
16
16
54
8
% L
% Met:
0
0
0
0
0
8
0
0
0
8
0
8
16
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
8
% N
% Pro:
0
0
8
8
8
0
39
0
8
0
0
8
0
0
8
% P
% Gln:
8
0
0
0
0
39
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
0
% R
% Ser:
24
0
8
8
8
0
0
8
0
8
31
0
16
8
0
% S
% Thr:
0
0
8
0
8
0
0
0
8
0
24
0
0
8
47
% T
% Val:
0
0
62
0
24
0
8
0
0
8
16
0
16
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
47
0
8
0
39
39
39
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _