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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN1
All Species:
18.18
Human Site:
Y33
Identified Species:
33.33
UniProt:
P35523
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35523
NP_000074.2
988
108756
Y33
P
F
E
H
C
T
S
Y
G
L
P
S
E
N
G
Chimpanzee
Pan troglodytes
XP_527935
988
108838
Y33
P
F
E
H
C
T
S
Y
G
L
P
S
E
N
G
Rhesus Macaque
Macaca mulatta
XP_001092282
736
80740
Dog
Lupus familis
XP_859634
871
95882
L34
E
E
A
A
R
I
R
L
G
G
P
E
T
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64347
994
109776
Y33
P
F
E
H
C
T
S
Y
G
L
P
S
E
N
G
Rat
Rattus norvegicus
P35524
994
110055
Y33
P
F
E
H
C
T
S
Y
G
L
P
S
E
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506417
871
95443
Y36
P
F
E
H
C
T
S
Y
G
L
P
S
D
G
R
Chicken
Gallus gallus
XP_425521
996
111070
E34
T
R
Y
G
I
P
L
E
A
G
R
E
A
G
G
Frog
Xenopus laevis
Q9W701
689
76782
Zebra Danio
Brachydanio rerio
XP_695866
879
96751
Y33
C
L
A
R
V
Q
R
Y
I
V
T
K
L
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
R52
E
K
F
I
C
Q
L
R
K
R
R
N
S
A
M
Honey Bee
Apis mellifera
XP_392015
919
102193
E33
R
R
K
Y
D
S
R
E
E
D
L
R
K
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
72.4
49.7
N.A.
87.4
87.8
N.A.
63.8
65.8
32.4
56.3
N.A.
34.9
36
N.A.
N.A.
Protein Similarity:
100
99.8
72.9
64
N.A.
91.4
91.9
N.A.
71.3
77.1
47.4
68.3
N.A.
51.9
52.4
N.A.
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
100
100
N.A.
80
6.6
0
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
0
13.3
N.A.
100
100
N.A.
86.6
6.6
0
13.3
N.A.
13.3
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
8
0
0
0
0
8
0
0
0
8
8
0
% A
% Cys:
8
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% D
% Glu:
16
8
39
0
0
0
0
16
8
0
0
16
31
0
8
% E
% Phe:
0
39
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
47
16
0
0
0
24
39
% G
% His:
0
0
0
39
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
8
8
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
8
0
0
8
8
0
0
% K
% Leu:
0
8
0
0
0
0
16
8
0
39
8
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
31
0
% N
% Pro:
39
0
0
0
0
8
0
0
0
0
47
0
0
0
0
% P
% Gln:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
0
8
8
0
24
8
0
8
16
8
0
0
24
% R
% Ser:
0
0
0
0
0
8
39
0
0
0
0
39
8
8
0
% S
% Thr:
8
0
0
0
0
39
0
0
0
0
8
0
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
8
8
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _