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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAU All Species: 34.85
Human Site: T12 Identified Species: 76.67
UniProt: P35544 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35544 NP_001988.1 74 7760 T12 V R A Q E L H T F E V T G Q E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118998 102 10621 T12 V C A Q E L H T L E V T G Q E
Dog Lupus familis XP_540869 133 14367 T12 V R A Q E L H T L E V T G Q E
Cat Felis silvestris
Mouse Mus musculus P35545 74 7767 T12 V R A Q E L H T L E V T G Q E
Rat Rattus norvegicus Q05474 74 7723 T12 V R A Q E L H T L E V T G Q E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512334 133 14415 T12 V R A R D L H T L Q V T G Q E
Chicken Gallus gallus
Frog Xenopus laevis NP_001089611 133 14493 T12 V R G Q S L H T L E V S G Q E
Zebra Danio Brachydanio rerio NP_957031 133 14606 T12 L R A Q S L H T L E V S G N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P14792 76 8520 T14 T L T G K T I T L E V E A S D
Sea Urchin Strong. purpuratus XP_783271 137 15081 T16 V R A D E T H T L E V T G E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59263 76 8506 T14 T L T G K T I T L E V E S S D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 53.3 N.A. 95.9 97.3 N.A. 45.8 N.A. 39.8 34.5 N.A. N.A. N.A. 35.5 27.7
Protein Similarity: 100 N.A. 66.6 54.8 N.A. 97.3 98.6 N.A. 49.6 N.A. 47.3 45.8 N.A. N.A. N.A. 55.2 35.7
P-Site Identity: 100 N.A. 86.6 93.3 N.A. 93.3 93.3 N.A. 73.3 N.A. 73.3 66.6 N.A. N.A. N.A. 20 73.3
P-Site Similarity: 100 N.A. 86.6 93.3 N.A. 93.3 93.3 N.A. 93.3 N.A. 80 80 N.A. N.A. N.A. 33.3 80
Percent
Protein Identity: N.A. N.A. N.A. 35.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 73 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 19 % D
% Glu: 0 0 0 0 55 0 0 0 0 91 0 19 0 10 82 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 19 0 0 0 0 0 0 0 0 82 0 0 % G
% His: 0 0 0 0 0 0 82 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 19 0 0 0 73 0 0 91 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 64 0 0 0 0 0 10 0 0 0 64 0 % Q
% Arg: 0 73 0 10 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 19 0 0 0 0 0 0 19 10 19 0 % S
% Thr: 19 0 19 0 0 28 0 100 0 0 0 64 0 0 0 % T
% Val: 73 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _