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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAU All Species: 32.42
Human Site: T53 Identified Species: 71.33
UniProt: P35544 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35544 NP_001988.1 74 7760 T53 A P L E D E A T L G Q C G V E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001118998 102 10621 T53 T P L E D E A T M G Q C G V E
Dog Lupus familis XP_540869 133 14367 T53 S P L E D E A T L G Q C G V E
Cat Felis silvestris
Mouse Mus musculus P35545 74 7767 T53 S P L E D E A T L G Q C G V E
Rat Rattus norvegicus Q05474 74 7723 T53 S P L E D E A T L G Q C G V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512334 133 14415 I53 S P L E D E A I L A Q C G V E
Chicken Gallus gallus
Frog Xenopus laevis NP_001089611 133 14493 T53 S P L S E E H T L Q Q C G V C
Zebra Danio Brachydanio rerio NP_957031 133 14606 T53 A P L Q D D S T L L N C G I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P14792 76 8520 T55 K Q L E D G R T L S D Y N I Q
Sea Urchin Strong. purpuratus XP_783271 137 15081 T57 A P L D E D I T L S Q N G L V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P59263 76 8506 T55 K Q L E D G R T L A D Y N I Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 53.3 N.A. 95.9 97.3 N.A. 45.8 N.A. 39.8 34.5 N.A. N.A. N.A. 35.5 27.7
Protein Similarity: 100 N.A. 66.6 54.8 N.A. 97.3 98.6 N.A. 49.6 N.A. 47.3 45.8 N.A. N.A. N.A. 55.2 35.7
P-Site Identity: 100 N.A. 86.6 93.3 N.A. 93.3 93.3 N.A. 80 N.A. 60 53.3 N.A. N.A. N.A. 33.3 46.6
P-Site Similarity: 100 N.A. 93.3 100 N.A. 100 100 N.A. 86.6 N.A. 73.3 80 N.A. N.A. N.A. 46.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. 35.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 55.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 0 0 0 0 55 0 0 19 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 73 0 0 10 % C
% Asp: 0 0 0 10 82 19 0 0 0 0 19 0 0 0 0 % D
% Glu: 0 0 0 73 19 64 0 0 0 0 0 0 0 0 55 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 19 0 0 0 46 0 0 82 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 0 0 0 28 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 91 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 10 19 0 0 % N
% Pro: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 19 0 10 0 0 0 0 0 10 73 0 0 0 19 % Q
% Arg: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % R
% Ser: 46 0 0 10 0 0 10 0 0 19 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 91 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 64 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _