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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSX2
All Species:
15.76
Human Site:
S12
Identified Species:
28.89
UniProt:
P35548
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35548
NP_002440.2
267
28867
S12
S
K
G
N
D
L
F
S
P
D
E
E
G
P
A
Chimpanzee
Pan troglodytes
A2T764
267
28880
S12
S
K
G
N
D
L
F
S
P
D
E
E
G
P
A
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
A44
M
G
A
D
E
E
G
A
K
P
K
V
S
P
S
Dog
Lupus familis
XP_545946
236
25066
L13
S
P
G
P
G
E
R
L
V
A
S
E
G
A
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q03358
267
28897
S12
T
K
G
G
D
L
F
S
S
D
E
E
G
P
A
Rat
Rattus norvegicus
P52953
139
15820
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512652
302
32580
A12
E
R
R
P
L
S
D
A
E
V
E
G
V
Y
V
Chicken
Gallus gallus
P28362
259
28217
S12
S
K
A
K
E
V
F
S
S
D
E
E
G
P
A
Frog
Xenopus laevis
P35993
291
32275
S40
R
R
I
K
E
D
L
S
S
D
E
E
G
Q
V
Zebra Danio
Brachydanio rerio
Q01704
226
25849
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15857
79
9464
Nematode Worm
Caenorhab. elegans
Q09604
225
25209
Sea Urchin
Strong. purpuratus
NP_999778
286
31115
S22
T
R
P
H
H
S
L
S
P
V
T
A
I
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
59.2
56.9
N.A.
92.1
50.9
N.A.
50.3
82.4
58.7
52.4
N.A.
N.A.
26.2
34.4
41.9
Protein Similarity:
100
98.8
67
63.6
N.A.
95.5
51.3
N.A.
55.6
86.8
69.7
61.4
N.A.
N.A.
28.4
46.8
52.8
P-Site Identity:
100
100
6.6
26.6
N.A.
80
0
N.A.
6.6
66.6
33.3
0
N.A.
N.A.
0
0
13.3
P-Site Similarity:
100
100
40
26.6
N.A.
86.6
0
N.A.
20
80
46.6
0
N.A.
N.A.
0
0
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
16
0
8
0
8
0
8
31
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
24
8
8
0
0
39
0
0
0
0
0
% D
% Glu:
8
0
0
0
24
16
0
0
8
0
47
47
0
0
0
% E
% Phe:
0
0
0
0
0
0
31
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
31
8
8
0
8
0
0
0
0
8
47
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
31
0
16
0
0
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
24
16
8
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
16
0
0
0
0
24
8
0
0
0
39
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
8
24
8
0
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
31
0
0
0
0
16
0
47
24
0
8
0
8
8
8
% S
% Thr:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
16
0
8
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _