Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSX2 All Species: 12.73
Human Site: S91 Identified Species: 23.33
UniProt: P35548 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35548 NP_002440.2 267 28867 S91 H G A R E A H S P G P L V K P
Chimpanzee Pan troglodytes A2T764 267 28880 S91 H G A R E A H S P G P L V K P
Rhesus Macaque Macaca mulatta Q2VL87 297 30903 G115 P L G H F S V G G L L K L P E
Dog Lupus familis XP_545946 236 25066 T76 S P E K P E R T P W M Q N P R
Cat Felis silvestris
Mouse Mus musculus Q03358 267 28897 S91 H G V R D A H S P G P L V K P
Rat Rattus norvegicus P52953 139 15820
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512652 302 32580 A81 G F V G L G S A A K P S W P G
Chicken Gallus gallus P28362 259 28217 P83 G S R D A H S P P G A L T K T
Frog Xenopus laevis P35993 291 32275 S109 L G I R D S P S P L G S Q K G
Zebra Danio Brachydanio rerio Q01704 226 25849 E70 P V K S E S P E P D D C T S W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera P15857 79 9464
Nematode Worm Caenorhab. elegans Q09604 225 25209 T69 V M I Y F A Q T G N R L P I V
Sea Urchin Strong. purpuratus NP_999778 286 31115 C127 S T D S T G R C S S P T T Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 59.2 56.9 N.A. 92.1 50.9 N.A. 50.3 82.4 58.7 52.4 N.A. N.A. 26.2 34.4 41.9
Protein Similarity: 100 98.8 67 63.6 N.A. 95.5 51.3 N.A. 55.6 86.8 69.7 61.4 N.A. N.A. 28.4 46.8 52.8
P-Site Identity: 100 100 0 6.6 N.A. 86.6 0 N.A. 6.6 26.6 33.3 13.3 N.A. N.A. 0 13.3 6.6
P-Site Similarity: 100 100 13.3 20 N.A. 93.3 0 N.A. 13.3 26.6 46.6 20 N.A. N.A. 0 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 8 31 0 8 8 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % C
% Asp: 0 0 8 8 16 0 0 0 0 8 8 0 0 0 0 % D
% Glu: 0 0 8 0 24 8 0 8 0 0 0 0 0 0 8 % E
% Phe: 0 8 0 0 16 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 16 31 8 8 0 16 0 8 16 31 8 0 0 0 16 % G
% His: 24 0 0 8 0 8 24 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 16 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 0 0 8 8 0 0 0 0 0 8 0 8 0 39 0 % K
% Leu: 8 8 0 0 8 0 0 0 0 16 8 39 8 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 16 8 0 0 8 0 16 8 54 0 39 0 8 24 24 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 8 8 8 0 % Q
% Arg: 0 0 8 31 0 0 16 0 0 0 8 0 0 0 8 % R
% Ser: 16 8 0 16 0 24 16 31 8 8 0 16 0 8 0 % S
% Thr: 0 8 0 0 8 0 0 16 0 0 0 8 24 0 16 % T
% Val: 8 8 16 0 0 0 8 0 0 0 0 0 24 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 8 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _