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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSX2
All Species:
2.12
Human Site:
T129
Identified Species:
3.89
UniProt:
P35548
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35548
NP_002440.2
267
28867
T129
Y
S
P
P
P
R
H
T
S
P
T
T
C
T
L
Chimpanzee
Pan troglodytes
A2T764
267
28880
M129
Y
S
P
P
P
R
H
M
S
P
T
T
C
T
L
Rhesus Macaque
Macaca mulatta
Q2VL87
297
30903
L153
S
P
P
P
A
R
R
L
S
P
P
A
C
T
L
Dog
Lupus familis
XP_545946
236
25066
T114
K
P
R
T
P
F
T
T
A
Q
L
L
A
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q03358
267
28897
M129
Y
S
P
P
P
R
H
M
S
P
T
T
C
T
L
Rat
Rattus norvegicus
P52953
139
15820
F21
N
R
K
P
R
T
P
F
T
T
S
Q
L
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512652
302
32580
P119
T
N
R
K
P
R
T
P
F
T
T
S
Q
L
L
Chicken
Gallus gallus
P28362
259
28217
L121
Y
S
P
P
P
R
H
L
S
P
T
A
C
T
L
Frog
Xenopus laevis
P35993
291
32275
L147
Y
S
P
P
P
R
H
L
S
P
S
S
C
T
L
Zebra Danio
Brachydanio rerio
Q01704
226
25849
T108
R
K
P
R
T
P
F
T
T
S
Q
L
L
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
P15857
79
9464
Nematode Worm
Caenorhab. elegans
Q09604
225
25209
P107
S
S
Q
R
E
D
S
P
T
S
D
D
A
K
I
Sea Urchin
Strong. purpuratus
NP_999778
286
31115
G165
E
I
R
P
P
F
A
G
P
K
V
Q
C
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
59.2
56.9
N.A.
92.1
50.9
N.A.
50.3
82.4
58.7
52.4
N.A.
N.A.
26.2
34.4
41.9
Protein Similarity:
100
98.8
67
63.6
N.A.
95.5
51.3
N.A.
55.6
86.8
69.7
61.4
N.A.
N.A.
28.4
46.8
52.8
P-Site Identity:
100
93.3
53.3
13.3
N.A.
93.3
6.6
N.A.
26.6
86.6
80
20
N.A.
N.A.
0
6.6
33.3
P-Site Similarity:
100
93.3
53.3
20
N.A.
93.3
20
N.A.
40
86.6
93.3
26.6
N.A.
N.A.
0
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
0
8
0
0
16
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
16
8
8
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
39
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
8
8
8
0
0
0
0
0
8
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
0
0
24
0
0
8
16
16
24
70
% L
% Met:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
54
62
62
8
8
16
8
47
8
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
8
16
8
0
0
% Q
% Arg:
8
8
24
16
8
54
8
0
0
0
0
0
0
0
0
% R
% Ser:
16
47
0
0
0
0
8
0
47
16
16
16
0
0
0
% S
% Thr:
8
0
0
8
8
8
16
24
24
16
39
24
0
54
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _