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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
26.67
Human Site:
S2564
Identified Species:
53.33
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
S2564
S
L
D
Q
T
G
S
S
C
E
D
V
D
E
C
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
S2697
S
L
D
Q
T
G
S
S
C
E
D
V
D
E
C
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
S2564
S
L
D
Q
T
G
S
S
C
E
D
V
D
E
C
Dog
Lupus familis
XP_535468
2871
311835
S2564
S
L
D
Q
S
G
A
S
C
E
D
V
D
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
S2564
S
L
D
Q
S
G
A
S
C
E
D
V
D
E
C
Rat
Rattus norvegicus
Q00918
1712
186581
E1424
D
E
C
L
L
F
G
E
E
I
C
K
N
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
S2608
S
L
D
Q
T
G
L
S
C
E
D
V
D
E
C
Frog
Xenopus laevis
P21783
2524
275106
S2236
H
L
T
S
M
P
E
S
Q
L
G
M
N
H
I
Zebra Danio
Brachydanio rerio
P46530
2437
262289
V2149
R
K
P
G
G
K
G
V
G
G
K
D
S
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
A2401
G
M
G
G
L
S
G
A
G
N
G
N
S
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
V3272
S
V
P
G
S
L
C
V
L
D
Y
C
S
D
V
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
T2421
L
L
S
E
D
G
L
T
C
R
D
V
N
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
86.6
N.A.
86.6
0
N.A.
N.A.
93.3
13.3
0
N.A.
0
N.A.
6.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
N.A.
93.3
26.6
0
N.A.
13.3
N.A.
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
9
0
59
0
9
9
0
0
59
% C
% Asp:
9
0
50
0
9
0
0
0
0
9
59
9
50
9
0
% D
% Glu:
0
9
0
9
0
0
9
9
9
50
0
0
0
59
9
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
25
9
59
25
0
17
9
17
0
0
17
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
0
9
0
0
0
9
0
0
0
0
9
9
0
0
9
% K
% Leu:
9
67
0
9
17
9
17
0
9
9
0
0
0
0
0
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
9
25
0
0
% N
% Pro:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
50
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
59
0
9
9
25
9
25
59
0
0
0
0
25
0
0
% S
% Thr:
0
0
9
0
34
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
17
0
0
0
59
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _