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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
19.39
Human Site:
S2709
Identified Species:
38.79
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
S2709
S
G
E
M
D
D
N
S
L
S
P
E
A
C
Y
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
S2842
S
G
E
M
D
D
N
S
L
S
P
E
A
C
Y
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
S2709
S
G
E
M
D
D
N
S
L
S
P
E
A
C
Y
Dog
Lupus familis
XP_535468
2871
311835
S2709
S
G
E
M
D
D
N
S
L
S
P
E
A
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
S2709
S
S
E
M
D
D
N
S
L
S
P
E
A
C
Y
Rat
Rattus norvegicus
Q00918
1712
186581
D1560
C
A
L
C
P
M
K
D
S
D
D
Y
A
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
N2768
L
S
G
E
M
D
D
N
S
L
S
P
E
A
C
Frog
Xenopus laevis
P21783
2524
275106
Q2372
Q
P
H
L
M
Q
A
Q
Q
M
Q
Q
Q
Q
N
Zebra Danio
Brachydanio rerio
P46530
2437
262289
L2285
G
M
L
M
P
T
M
L
S
A
T
N
M
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
P2537
A
I
M
Q
T
I
S
P
Q
Q
Q
Q
Q
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
T3470
G
G
A
W
P
W
S
T
L
E
G
S
A
S
S
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
N2569
P
C
Q
Y
S
C
D
N
T
D
G
S
F
S
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
N.A.
6.6
0
6.6
N.A.
0
N.A.
20
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
N.A.
20
13.3
13.3
N.A.
20
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
0
0
9
0
0
9
0
0
59
9
0
% A
% Cys:
9
9
0
9
0
9
0
0
0
0
0
0
0
42
17
% C
% Asp:
0
0
0
0
42
50
17
9
0
17
9
0
0
0
0
% D
% Glu:
0
0
42
9
0
0
0
0
0
9
0
42
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
17
42
9
0
0
0
0
0
0
0
17
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
17
9
0
0
0
9
50
9
0
0
0
0
9
% L
% Met:
0
9
9
50
17
9
9
0
0
9
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
42
17
0
0
0
9
0
0
9
% N
% Pro:
9
9
0
0
25
0
0
9
0
0
42
9
0
9
0
% P
% Gln:
9
0
9
9
0
9
0
9
17
9
17
17
17
25
17
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
42
17
0
0
9
0
17
42
25
42
9
17
0
17
9
% S
% Thr:
0
0
0
0
9
9
0
9
9
0
9
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
42
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _