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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
18.48
Human Site:
S2739
Identified Species:
36.97
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
S2739
S
T
N
E
T
D
A
S
N
I
E
D
Q
S
E
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
S2872
S
T
N
E
T
D
A
S
N
I
E
D
Q
S
E
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
S2739
S
T
N
E
T
D
A
S
N
I
E
D
Q
S
E
Dog
Lupus familis
XP_535468
2871
311835
S2739
S
A
N
E
T
D
A
S
N
I
E
D
Q
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
S2739
S
T
N
E
T
D
A
S
D
I
Q
D
G
S
E
Rat
Rattus norvegicus
Q00918
1712
186581
Q1590
A
L
V
D
F
S
E
Q
Y
G
P
E
T
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
N2798
R
S
T
N
E
T
A
N
E
A
E
D
E
Q
E
Frog
Xenopus laevis
P21783
2524
275106
S2402
T
T
S
T
H
I
N
S
P
F
C
S
S
D
I
Zebra Danio
Brachydanio rerio
P46530
2437
262289
N2315
S
H
M
I
A
H
Q
N
M
A
P
M
Q
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
Q2567
Q
Q
Q
Q
Q
Q
Q
Q
Q
L
G
G
L
E
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
P3500
Y
Y
P
D
I
G
I
P
R
A
K
L
K
S
G
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
P2599
T
D
R
D
S
V
Q
P
C
Y
S
C
N
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
N.A.
26.6
13.3
13.3
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
20
N.A.
N.A.
46.6
26.6
26.6
N.A.
13.3
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
0
50
0
0
25
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
9
9
0
0
0
% C
% Asp:
0
9
0
25
0
42
0
0
9
0
0
50
0
17
0
% D
% Glu:
0
0
0
42
9
0
9
0
9
0
42
9
9
9
50
% E
% Phe:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
9
0
0
0
9
9
9
9
0
9
% G
% His:
0
9
0
0
9
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
9
9
9
9
0
0
42
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
9
0
9
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% M
% Asn:
0
0
42
9
0
0
9
17
34
0
0
0
9
0
0
% N
% Pro:
0
0
9
0
0
0
0
17
9
0
17
0
0
9
9
% P
% Gln:
9
9
9
9
9
9
25
17
9
0
9
0
42
9
17
% Q
% Arg:
9
0
9
0
0
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
50
9
9
0
9
9
0
50
0
0
9
9
9
42
0
% S
% Thr:
17
42
9
9
42
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _