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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
19.39
Human Site:
S722
Identified Species:
38.79
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
S722
P
G
M
T
S
A
G
S
D
I
N
E
C
A
L
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
S855
P
G
M
T
S
A
G
S
D
I
N
E
C
A
L
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
S722
P
G
M
T
S
A
G
S
D
I
N
E
C
A
L
Dog
Lupus familis
XP_535468
2871
311835
S722
P
G
M
T
S
A
G
S
D
I
N
E
C
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
T722
P
G
M
T
S
A
G
T
D
I
N
E
C
A
L
Rat
Rattus norvegicus
Q00918
1712
186581
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
N767
S
G
M
T
A
G
G
N
D
I
N
E
C
L
L
Frog
Xenopus laevis
P21783
2524
275106
D544
K
N
G
A
K
C
L
D
G
P
N
S
Y
T
C
Zebra Danio
Brachydanio rerio
P46530
2437
262289
S457
M
D
V
N
E
C
K
S
N
P
C
Q
N
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
K638
Y
T
G
Y
I
C
Q
K
Q
I
N
E
C
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
R1063
E
C
V
E
T
A
F
R
Y
T
D
G
S
C
R
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
E676
G
D
Q
G
R
C
Y
E
C
P
Q
E
G
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
66.6
6.6
6.6
N.A.
26.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
80
6.6
26.6
N.A.
26.6
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
50
0
0
0
0
0
0
0
42
9
% A
% Cys:
0
9
0
0
0
34
0
0
9
0
9
0
59
9
9
% C
% Asp:
0
17
0
0
0
0
0
9
50
0
9
0
0
9
0
% D
% Glu:
9
0
0
9
9
0
0
9
0
0
0
67
0
9
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
50
17
9
0
9
50
0
9
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
59
0
0
0
0
0
% I
% Lys:
9
0
0
0
9
0
9
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
50
% L
% Met:
9
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
9
9
0
67
0
9
0
0
% N
% Pro:
42
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
9
0
9
9
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% R
% Ser:
9
0
0
0
42
0
0
42
0
0
0
9
9
9
9
% S
% Thr:
0
9
0
50
9
0
0
9
0
9
0
0
0
9
0
% T
% Val:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
9
0
9
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _