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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
18.79
Human Site:
Y1004
Identified Species:
37.58
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
Y1004
P
M
R
N
T
P
E
Y
E
E
L
C
P
R
G
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
Y1137
P
M
R
N
T
P
E
Y
E
E
L
C
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
Y1004
P
M
R
N
T
P
E
Y
E
E
L
C
P
R
G
Dog
Lupus familis
XP_535468
2871
311835
Y1004
P
V
R
N
T
P
E
Y
E
E
L
C
P
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
Y1004
P
L
R
N
S
R
E
Y
E
E
L
C
P
R
G
Rat
Rattus norvegicus
Q00918
1712
186581
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
E1049
L
K
G
S
P
E
F
E
A
L
C
P
R
G
A
Frog
Xenopus laevis
P21783
2524
275106
A810
G
T
C
I
D
D
V
A
G
Y
K
C
N
C
M
Zebra Danio
Brachydanio rerio
P46530
2437
262289
C723
N
E
C
S
S
N
P
C
I
H
G
S
C
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
I908
G
R
Y
C
D
E
D
I
D
E
C
S
L
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
T1365
A
R
K
L
S
I
N
T
F
A
I
G
V
T
D
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
D948
Q
E
G
G
Y
L
C
D
C
F
V
G
F
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
93.3
N.A.
80
0
N.A.
N.A.
0
6.6
0
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
0
N.A.
N.A.
6.6
6.6
13.3
N.A.
20
N.A.
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
9
9
0
0
0
0
9
% A
% Cys:
0
0
17
9
0
0
9
9
9
0
17
50
9
9
0
% C
% Asp:
0
0
0
0
17
9
9
9
9
0
0
0
0
0
17
% D
% Glu:
0
17
0
0
0
17
42
9
42
50
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
9
9
0
0
9
0
0
% F
% Gly:
17
0
17
9
0
0
0
0
9
0
9
17
0
9
42
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
0
9
9
0
9
0
0
0
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
9
9
0
9
0
9
0
0
0
9
42
0
9
9
0
% L
% Met:
0
25
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
9
0
0
42
0
9
9
0
0
0
0
0
9
0
0
% N
% Pro:
42
0
0
0
9
34
9
0
0
0
0
9
42
0
9
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
42
0
0
9
0
0
0
0
0
0
9
50
0
% R
% Ser:
0
0
0
17
25
0
0
0
0
0
0
17
0
9
9
% S
% Thr:
0
9
0
0
34
0
0
9
0
0
0
0
0
9
0
% T
% Val:
0
9
0
0
0
0
9
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
0
0
42
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _