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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN1
All Species:
22.73
Human Site:
Y2853
Identified Species:
45.45
UniProt:
P35555
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35555
NP_000129.2
2871
312298
Y2853
E
D
K
Y
D
K
D
Y
L
S
G
E
L
G
D
Chimpanzee
Pan troglodytes
XP_001149266
3004
325935
Y2986
E
D
K
Y
D
K
D
Y
L
S
G
E
L
G
D
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
Y2853
E
D
K
Y
D
K
D
Y
L
S
G
E
L
G
D
Dog
Lupus familis
XP_535468
2871
311835
Y2853
E
D
K
Y
D
K
D
Y
L
S
G
E
L
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q61554
2871
312248
Y2853
E
D
R
Y
D
K
D
Y
L
S
G
E
L
G
D
Rat
Rattus norvegicus
Q00918
1712
186581
L1703
C
T
P
L
N
T
A
L
N
L
D
K
D
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413815
2930
318727
Y2912
E
E
K
H
D
K
D
Y
L
S
G
E
L
G
D
Frog
Xenopus laevis
P21783
2524
275106
Q2515
P
P
T
S
M
Q
P
Q
R
T
H
I
P
E
A
Zebra Danio
Brachydanio rerio
P46530
2437
262289
Q2428
S
S
P
P
T
S
M
Q
M
N
H
I
P
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
G2691
N
N
L
Y
I
S
G
G
H
Q
A
N
K
G
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34576
3767
417272
R3692
E
E
E
F
S
I
G
R
A
R
G
M
A
A
A
Sea Urchin
Strong. purpuratus
XP_001188280
2737
299049
P2722
V
Q
T
V
V
E
E
P
V
A
M
Q
I
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.5
99.4
97.3
N.A.
95.7
23.2
N.A.
N.A.
82.5
22.2
22
N.A.
20.2
N.A.
22.2
34
Protein Similarity:
100
95.5
99.6
98.6
N.A.
98.3
35.2
N.A.
N.A.
89.4
36.4
35
N.A.
34
N.A.
36
47.6
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
N.A.
86.6
0
0
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
N.A.
100
13.3
13.3
N.A.
20
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
9
9
0
9
9
25
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
0
50
0
50
0
0
0
9
0
9
0
59
% D
% Glu:
59
17
9
0
0
9
9
0
0
0
0
50
0
17
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
9
0
0
59
0
0
59
0
% G
% His:
0
0
0
9
0
0
0
0
9
0
17
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
17
9
0
0
% I
% Lys:
0
0
42
0
0
50
0
0
0
0
0
9
9
0
0
% K
% Leu:
0
0
9
9
0
0
0
9
50
9
0
0
50
0
0
% L
% Met:
0
0
0
0
9
0
9
0
9
0
9
9
0
0
0
% M
% Asn:
9
9
0
0
9
0
0
0
9
9
0
9
0
0
0
% N
% Pro:
9
9
17
9
0
0
9
9
0
0
0
0
17
0
0
% P
% Gln:
0
9
0
0
0
9
0
17
0
9
0
9
0
9
0
% Q
% Arg:
0
0
9
0
0
0
0
9
9
9
0
0
0
0
0
% R
% Ser:
9
9
0
9
9
17
0
0
0
50
0
0
0
9
9
% S
% Thr:
0
9
17
0
9
9
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
0
9
9
0
0
0
9
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _