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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBN2
All Species:
9.39
Human Site:
S445
Identified Species:
25.83
UniProt:
P35556
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35556
NP_001990.2
2912
314775
S445
G
G
N
G
F
A
P
S
G
N
G
N
G
Y
G
Chimpanzee
Pan troglodytes
XP_526999
2912
314837
S445
G
G
N
G
F
A
P
S
G
N
G
N
G
Y
G
Rhesus Macaque
Macaca mulatta
XP_001113107
2871
312351
P416
I
P
P
V
L
P
V
P
P
G
F
P
P
G
P
Dog
Lupus familis
XP_538612
2921
315621
S456
G
G
N
G
F
A
P
S
G
N
G
Y
G
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61555
2907
313611
G445
G
S
N
G
N
G
Y
G
P
G
G
T
G
F
L
Rat
Rattus norvegicus
Q00918
1712
186581
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
P21783
2524
275106
C291
P
D
W
T
G
Q
Y
C
T
E
D
V
D
E
C
Zebra Danio
Brachydanio rerio
P46530
2437
262289
R204
E
V
G
S
Y
L
C
R
C
P
P
E
Y
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07207
2703
288835
T399
G
S
F
Y
C
Q
C
T
K
G
K
T
G
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
68.3
97.3
N.A.
95.7
22
N.A.
N.A.
N.A.
21.9
21.8
N.A.
21.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
81.1
98.6
N.A.
97.6
34.1
N.A.
N.A.
N.A.
36.6
35.5
N.A.
35.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
86.6
N.A.
33.3
0
N.A.
N.A.
N.A.
0
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
86.6
N.A.
40
0
N.A.
N.A.
N.A.
0
13.3
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
34
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
23
12
12
0
0
0
0
0
12
% C
% Asp:
0
12
0
0
0
0
0
0
0
0
12
0
12
0
0
% D
% Glu:
12
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% E
% Phe:
0
0
12
0
34
0
0
0
0
0
12
0
0
12
0
% F
% Gly:
56
34
12
45
12
12
0
12
34
34
45
0
56
12
45
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% K
% Leu:
0
0
0
0
12
12
0
0
0
0
0
0
0
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
45
0
12
0
0
0
0
34
0
23
0
0
0
% N
% Pro:
12
12
12
0
0
12
34
12
23
12
12
12
12
12
12
% P
% Gln:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
0
23
0
12
0
0
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
12
12
0
0
23
0
12
0
% T
% Val:
0
12
0
12
0
0
12
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
12
0
23
0
0
0
0
12
12
23
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _