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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PCK1 All Species: 21.21
Human Site: T178 Identified Species: 46.67
UniProt: P35558 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35558 NP_002582.3 622 69195 T178 R I M T R M G T P V L E A V G
Chimpanzee Pan troglodytes XP_514745 622 69186 T178 R I M T R M G T P V L E A L G
Rhesus Macaque Macaca mulatta XP_001086710 622 69152 T178 R I M T R M G T P V L E A L G
Dog Lupus familis XP_537379 640 70784 M196 R I M T R L G M P V L R A L G
Cat Felis silvestris
Mouse Mus musculus Q9Z2V4 622 69336 I178 R I M T R M G I S V L E A L G
Rat Rattus norvegicus P07379 622 69397 T178 R I M T R M G T S V L E A L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518084 681 75076 D237 R I M T R L G D P V L R A L G
Chicken Gallus gallus P05153 622 69510 T178 R M M T R M G T A A L K A L G
Frog Xenopus laevis NP_001079946 622 69844 T178 R I M T R I G T A V L E T L G
Zebra Danio Brachydanio rerio NP_999916 630 69674 K179 R I M T R M G K T V L S A L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20007 647 71111 A204 R I M T R M G A A V L R Q L A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.4 68.9 N.A. 90.8 90.8 N.A. 66 83.7 80.7 73 N.A. 62.4 N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.1 81.8 N.A. 95.8 95.8 N.A. 77.8 92.9 90.3 84.5 N.A. 75.1 N.A. N.A. N.A.
P-Site Identity: 100 93.3 93.3 73.3 N.A. 80 86.6 N.A. 73.3 66.6 73.3 73.3 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 93.3 N.A. 86.6 86.6 86.6 80 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 28 10 0 0 82 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 91 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 91 0 0 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 0 19 0 0 0 0 100 0 0 91 0 % L
% Met: 0 10 100 0 0 73 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 100 0 0 0 100 0 0 0 0 0 0 28 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 19 0 0 10 0 0 0 % S
% Thr: 0 0 0 100 0 0 0 55 10 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 91 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _