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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PC
All Species:
18.48
Human Site:
Y146
Identified Species:
45.19
UniProt:
P35575
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35575
NP_000142.1
357
40484
Y146
Q
G
K
I
K
P
T
Y
R
F
R
C
L
N
V
Chimpanzee
Pan troglodytes
XP_001155854
355
40704
S142
V
C
G
M
D
K
F
S
I
T
L
H
R
L
T
Rhesus Macaque
Macaca mulatta
XP_001112333
357
40503
Y146
R
G
K
K
K
P
T
Y
R
F
R
C
L
N
V
Dog
Lupus familis
XP_855553
357
40921
Y146
R
G
R
K
R
P
T
Y
R
F
R
C
L
N
I
Cat
Felis silvestris
Mouse
Mus musculus
P35576
357
40462
Y146
R
G
K
K
K
P
T
Y
G
F
R
C
L
N
V
Rat
Rattus norvegicus
P43428
357
40537
Y146
R
G
K
K
K
S
T
Y
G
F
R
C
L
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513875
355
40390
S142
L
S
Q
I
D
K
S
S
V
T
L
H
R
L
T
Chicken
Gallus gallus
XP_418136
1153
128847
W948
S
T
P
C
R
I
L
W
A
M
L
W
T
G
F
Frog
Xenopus laevis
NP_001080160
357
40483
L146
L
K
K
K
E
T
S
L
S
N
W
C
M
R
G
Zebra Danio
Brachydanio rerio
A1A5Z0
339
37984
T137
A
S
F
S
Q
A
Y
T
G
S
K
I
L
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
97.7
91.5
N.A.
88.2
86.8
N.A.
53.2
21.2
70
37.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.7
99.1
96.6
N.A.
94.1
93.8
N.A.
69.4
26.7
82.3
56.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
66.6
N.A.
80
73.3
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
93.3
93.3
N.A.
86.6
80
N.A.
20
13.3
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
10
0
10
0
0
0
0
0
0
0
60
0
0
0
% C
% Asp:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
50
0
0
0
0
10
% F
% Gly:
0
50
10
0
0
0
0
0
30
0
0
0
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% H
% Ile:
0
0
0
20
0
10
0
0
10
0
0
10
0
0
10
% I
% Lys:
0
10
50
50
40
20
0
0
0
0
10
0
0
0
0
% K
% Leu:
20
0
0
0
0
0
10
10
0
0
30
0
60
20
0
% L
% Met:
0
0
0
10
0
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
50
0
% N
% Pro:
0
0
10
0
0
40
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
40
0
10
0
20
0
0
0
30
0
50
0
20
10
0
% R
% Ser:
10
20
0
10
0
10
20
20
10
10
0
0
0
10
0
% S
% Thr:
0
10
0
0
0
10
50
10
0
20
0
0
10
0
20
% T
% Val:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
40
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _