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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYH9 All Species: 11.82
Human Site: S1435 Identified Species: 28.89
UniProt: P35579 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35579 NP_002464.1 1960 226532 S1435 D L D H Q R Q S A C N L E K K
Chimpanzee Pan troglodytes XP_001166502 1986 230140 V1452 D L D H Q R Q V A S N L E K K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536636 1976 229085 I1442 D L D H Q R Q I A S N L E K K
Cat Felis silvestris
Mouse Mus musculus Q8VDD5 1960 226354 S1435 D L D H Q R Q S V S N L E K K
Rat Rattus norvegicus Q62812 1961 226320 S1436 D L D H Q R Q S V S N L E K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508844 1972 227342 L1442 D L D N Q R Q L V S N L E K K
Chicken Gallus gallus P14105 1959 226485 T1435 D L D H Q R Q T V S N L E K K
Frog Xenopus laevis NP_001081846 1964 226791 I1435 D L D H Q R Q I V S N L E K K
Zebra Danio Brachydanio rerio XP_683046 1976 229358 I1445 D L D H Q R Q I V S N L E K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q99323 2057 236625 K1526 E L E A Q R T K V L E L E K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 77.5 N.A. 77.6 N.A. 97 96.1 N.A. 75.7 92.6 86.8 77.6 N.A. 58.2 N.A. N.A. N.A.
Protein Similarity: 100 88.1 N.A. 88.5 N.A. 98.5 98 N.A. 88.2 96.7 93.5 88.8 N.A. 75.4 N.A. N.A. N.A.
P-Site Identity: 100 86.6 N.A. 86.6 N.A. 86.6 86.6 N.A. 73.3 80 80 80 N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 N.A. 86.6 N.A. 86.6 86.6 N.A. 80 86.6 80 80 N.A. 60 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 30 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 90 0 90 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 0 0 10 0 100 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 100 100 % K
% Leu: 0 100 0 0 0 0 0 10 0 10 0 100 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 90 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 100 0 90 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 30 0 80 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 70 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _