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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYH10 All Species: 40.91
Human Site: T177 Identified Species: 100
UniProt: P35580 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35580 NP_005955.1 1976 228999 T177 E D Q S I L C T G E S G A G K
Chimpanzee Pan troglodytes XP_001166502 1986 230140 T177 E D Q S I L C T G E S G A G K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536636 1976 229085 T177 E D Q S I L C T G E S G A G K
Cat Felis silvestris
Mouse Mus musculus Q61879 1976 228978 T177 E D Q S I L C T G E S G A G K
Rat Rattus norvegicus Q9JLT0 1976 228947 T177 K D Q S I L C T G E S G A G K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508844 1972 227342 T177 E D Q S I L C T G E S G A G K
Chicken Gallus gallus P10587 1979 228777 T176 E D Q S I L C T G E S G A G K
Frog Xenopus laevis NP_001084034 1992 231076 T177 E D Q S I L C T G E S G A G K
Zebra Danio Brachydanio rerio XP_683046 1976 229358 T180 E D Q S I L C T G E S G A G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q99323 2057 236625 T224 E D Q S I L C T G E S G A G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 98.9 N.A. 99 98.7 N.A. 76.2 75.6 89.9 90 N.A. 59.7 N.A. N.A. N.A.
Protein Similarity: 100 99.5 N.A. 99.6 N.A. 99.5 99.2 N.A. 88.7 89 95.2 96 N.A. 76.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 93.3 N.A. 100 100 100 100 N.A. 100 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % A
% Cys: 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 % C
% Asp: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 90 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 100 0 100 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % K
% Leu: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 100 0 0 0 0 0 0 100 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _