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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPB2 All Species: 33.94
Human Site: Y566 Identified Species: 82.96
UniProt: P35606 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35606 NP_004757.1 906 102487 Y566 R T M Y L L G Y I P K D N R L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534283 906 102370 Y566 R T M Y L L G Y I P K D N R L
Cat Felis silvestris
Mouse Mus musculus O55029 905 102431 Y566 R T M Y L L G Y I P K D N R L
Rat Rattus norvegicus O35142 905 102533 Y566 R T M Y L L G Y I P K D N R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505405 1064 119826 Y715 R T M Y L L G Y I P K D N R L
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O62621 914 102694 Y568 R T M Y L L G Y V P K D N R I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20168 1000 111088 Y565 R P L Y L L G Y M A K E S R V
Sea Urchin Strong. purpuratus XP_001191382 1012 113829 W642 R D P S E Q K W K Q L A E L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAA0 920 103951 Y566 R P M Y L L G Y L A N Q S R V
Baker's Yeast Sacchar. cerevisiae P41811 889 99426 Y578 K E M Y L L G Y L A R D N K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99 N.A. 98.2 97.2 N.A. 81.7 N.A. N.A. N.A. N.A. 68.3 N.A. 58 62
Protein Similarity: 100 N.A. N.A. 99.5 N.A. 99 98.4 N.A. 83.2 N.A. N.A. N.A. N.A. 82.8 N.A. 73.5 74.4
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 86.6 N.A. 53.3 6.6
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 N.A. N.A. N.A. N.A. 100 N.A. 86.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 56.8 43.9 N.A.
Protein Similarity: N.A. N.A. N.A. 75.2 64.5 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 30 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 70 0 0 0 % D
% Glu: 0 10 0 0 10 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 10 % I
% Lys: 10 0 0 0 0 0 10 0 10 0 70 0 0 10 0 % K
% Leu: 0 0 10 0 90 90 0 0 20 0 10 0 0 10 50 % L
% Met: 0 0 80 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 0 70 0 0 % N
% Pro: 0 20 10 0 0 0 0 0 0 60 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 10 0 10 0 0 0 % Q
% Arg: 90 0 0 0 0 0 0 0 0 0 10 0 0 80 0 % R
% Ser: 0 0 0 10 0 0 0 0 0 0 0 0 20 0 0 % S
% Thr: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 90 0 0 0 90 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _