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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADD1 All Species: 16.36
Human Site: S669 Identified Species: 32.73
UniProt: P35611 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35611 NP_054908.2 737 80955 S669 E E A H R P P S P T E A P T E
Chimpanzee Pan troglodytes XP_001150699 737 80926 S669 E E A H R P P S P T E A P T E
Rhesus Macaque Macaca mulatta XP_001088348 737 80858 S669 E E A Q R P P S P T E A P T E
Dog Lupus familis XP_861791 742 81084 S676 S E A R E P P S P T G S P V A
Cat Felis silvestris
Mouse Mus musculus Q9QYC0 735 80628 D667 E E A H A S P D P T Q P P A E
Rat Rattus norvegicus Q63028 735 80337 D667 E E A H A S P D T T Q P L A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506605 579 62981 S514 P P S R A E A S A A A H P D P
Chicken Gallus gallus NP_001073198 733 80632 D667 E E G R C D E D V S K S Q T E
Frog Xenopus laevis NP_001081110 799 88008 D723 Q S V P C D R D I T K A P T E
Zebra Danio Brachydanio rerio NP_001073427 741 81714 L669 L R Q T L P D L T S D E A S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02645 1156 127921 S894 Q D S G L Y R S Y T F L P S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U9K0 732 82151 Y656 E E S V N T S Y M S Q S V V F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.1 91.9 N.A. 92.6 92.1 N.A. 66.4 85.2 75 76.3 N.A. 26.9 N.A. 31.3 N.A.
Protein Similarity: 100 99.7 99.3 94 N.A. 95.5 94.5 N.A. 69.7 90.6 82.8 85 N.A. 40.8 N.A. 50 N.A.
P-Site Identity: 100 100 93.3 53.3 N.A. 60 46.6 N.A. 13.3 26.6 33.3 13.3 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 100 93.3 60 N.A. 66.6 53.3 N.A. 20 46.6 46.6 33.3 N.A. 46.6 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 50 0 25 0 9 0 9 9 9 34 9 17 9 % A
% Cys: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 17 9 34 0 0 9 0 0 9 0 % D
% Glu: 59 67 0 0 9 9 9 0 0 0 25 9 0 0 67 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % F
% Gly: 0 0 9 9 0 0 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 34 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % K
% Leu: 9 0 0 0 17 0 0 9 0 0 0 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 9 9 0 9 0 42 50 0 42 0 0 17 67 0 9 % P
% Gln: 17 0 9 9 0 0 0 0 0 0 25 0 9 0 0 % Q
% Arg: 0 9 0 25 25 0 17 0 0 0 0 0 0 0 0 % R
% Ser: 9 9 25 0 0 17 9 50 0 25 0 25 0 17 0 % S
% Thr: 0 0 0 9 0 9 0 0 17 67 0 0 0 42 0 % T
% Val: 0 0 9 9 0 0 0 0 9 0 0 0 9 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 9 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _