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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADD1
All Species:
36.36
Human Site:
Y273
Identified Species:
72.73
UniProt:
P35611
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35611
NP_054908.2
737
80955
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Chimpanzee
Pan troglodytes
XP_001150699
737
80926
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Rhesus Macaque
Macaca mulatta
XP_001088348
737
80858
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Dog
Lupus familis
XP_861791
742
81084
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC0
735
80628
Y273
G
D
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Rat
Rattus norvegicus
Q63028
735
80337
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506605
579
62981
V143
I
L
R
N
H
G
L
V
S
V
G
E
T
V
E
Chicken
Gallus gallus
NP_001073198
733
80632
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
D
Frog
Xenopus laevis
NP_001081110
799
88008
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Zebra Danio
Brachydanio rerio
NP_001073427
741
81714
Y273
G
E
V
A
Y
H
D
Y
H
G
I
L
V
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02645
1156
127921
H275
K
V
I
L
L
T
N
H
G
A
L
C
C
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U9K0
732
82151
L268
F
D
E
I
I
A
N
L
G
D
K
N
V
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
91.9
N.A.
92.6
92.1
N.A.
66.4
85.2
75
76.3
N.A.
26.9
N.A.
31.3
N.A.
Protein Similarity:
100
99.7
99.3
94
N.A.
95.5
94.5
N.A.
69.7
90.6
82.8
85
N.A.
40.8
N.A.
50
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
6.6
93.3
100
100
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
33.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
75
0
9
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
17
0
0
0
0
75
0
0
9
0
0
0
75
9
% D
% Glu:
0
67
9
0
0
0
0
0
0
0
0
9
0
0
84
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
75
0
0
0
0
9
0
0
17
75
9
0
0
9
0
% G
% His:
0
0
0
0
9
75
0
9
75
0
0
0
0
0
0
% H
% Ile:
9
0
9
9
9
0
0
0
0
0
75
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
9
0
9
9
0
9
9
0
0
9
75
0
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
17
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
0
9
75
0
0
0
0
9
0
9
0
0
84
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
75
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _