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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADD2
All Species:
10.91
Human Site:
S592
Identified Species:
26.67
UniProt:
P35612
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35612
NP_001608.1
726
80854
S592
T
A
P
E
E
P
G
S
P
A
K
S
A
P
A
Chimpanzee
Pan troglodytes
XP_001143122
726
80832
S592
T
A
P
E
E
P
G
S
P
A
K
S
A
P
A
Rhesus Macaque
Macaca mulatta
XP_001100191
726
80838
S592
T
A
P
E
E
P
G
S
P
A
K
S
A
P
A
Dog
Lupus familis
XP_853066
722
79644
E588
G
E
K
E
T
P
A
E
G
P
G
S
P
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYB8
725
80623
K591
E
K
D
I
A
T
E
K
P
G
S
P
V
K
S
Rat
Rattus norvegicus
Q05764
725
80574
E591
E
K
D
A
A
T
E
E
P
G
S
P
V
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512778
707
79109
K573
Y
K
K
T
V
E
R
K
Q
Q
G
L
E
D
A
Chicken
Gallus gallus
NP_989434
709
78787
L575
K
T
I
E
R
K
Q
L
G
L
E
D
A
E
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02645
1156
127921
T981
S
S
P
T
P
T
A
T
Q
S
P
A
T
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U9K0
732
82151
V586
I
K
K
Y
V
D
M
V
K
A
K
N
S
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
92.1
N.A.
92.5
92.1
N.A.
54.9
56.3
N.A.
N.A.
N.A.
25.2
N.A.
27.4
N.A.
Protein Similarity:
100
99.8
99.8
95.4
N.A.
95.4
94.7
N.A.
74.5
73.4
N.A.
N.A.
N.A.
41.7
N.A.
50.1
N.A.
P-Site Identity:
100
100
100
20
N.A.
6.6
6.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
13.3
13.3
N.A.
6.6
20
N.A.
N.A.
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
10
20
0
20
0
0
40
0
10
40
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
10
0
0
0
0
0
10
0
10
0
% D
% Glu:
20
10
0
50
30
10
20
20
0
0
10
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
30
0
20
20
20
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
40
30
0
0
10
0
20
10
0
40
0
0
20
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
40
0
10
40
0
0
50
10
10
20
10
30
0
% P
% Gln:
0
0
0
0
0
0
10
0
20
10
0
0
0
10
10
% Q
% Arg:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
0
0
0
30
0
10
20
40
10
0
40
% S
% Thr:
30
10
0
20
10
30
0
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
20
0
0
10
0
0
0
0
20
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _