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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADD2 All Species: 23.94
Human Site: T460 Identified Species: 58.52
UniProt: P35612 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35612 NP_001608.1 726 80854 T460 M G S P R P K T T W M K A D E
Chimpanzee Pan troglodytes XP_001143122 726 80832 T460 M G S P R P K T T W M K A D E
Rhesus Macaque Macaca mulatta XP_001100191 726 80838 T460 M G S P R P K T T W M K A D E
Dog Lupus familis XP_853066 722 79644 T460 M G S P R P K T T W M K A D E
Cat Felis silvestris
Mouse Mus musculus Q9QYB8 725 80623 T460 M G S P R P K T T W M K A D E
Rat Rattus norvegicus Q05764 725 80574 T460 M G S P R P K T T W M K A D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512778 707 79109 N444 T R W L N S P N T Y M K V N V
Chicken Gallus gallus NP_989434 709 78787 N444 T R W L N S P N T Y L K V N V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q02645 1156 127921 S630 G T K K Y P Q S E P E T E H Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U9K0 732 82151 V455 P K K I T K W V H D V N V P S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.7 92.1 N.A. 92.5 92.1 N.A. 54.9 56.3 N.A. N.A. N.A. 25.2 N.A. 27.4 N.A.
Protein Similarity: 100 99.8 99.8 95.4 N.A. 95.4 94.7 N.A. 74.5 73.4 N.A. N.A. N.A. 41.7 N.A. 50.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 20 13.3 N.A. N.A. N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 33.3 N.A. N.A. N.A. 26.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 60 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 10 0 10 0 60 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 20 10 0 10 60 0 0 0 0 80 0 0 0 % K
% Leu: 0 0 0 20 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 60 0 0 0 0 0 0 0 0 0 70 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 0 20 0 0 0 10 0 20 0 % N
% Pro: 10 0 0 60 0 70 20 0 0 10 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % Q
% Arg: 0 20 0 0 60 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 60 0 0 20 0 10 0 0 0 0 0 0 10 % S
% Thr: 20 10 0 0 10 0 0 60 80 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 10 0 30 0 20 % V
% Trp: 0 0 20 0 0 0 10 0 0 60 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 20 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _