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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRBK2
All Species:
4.55
Human Site:
S451
Identified Species:
8.33
UniProt:
P35626
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35626
NP_005151.2
688
79710
S451
S
Q
E
V
K
E
H
S
F
F
K
G
V
D
W
Chimpanzee
Pan troglodytes
XP_508589
669
77389
P431
A
Q
E
V
K
E
S
P
F
F
R
S
L
D
W
Rhesus Macaque
Macaca mulatta
XP_001104308
669
77662
S432
S
Q
E
V
K
E
H
S
F
F
K
G
V
D
W
Dog
Lupus familis
XP_543453
669
77588
I432
A
Q
E
V
K
E
H
I
F
F
K
G
I
D
W
Cat
Felis silvestris
Mouse
Mus musculus
Q3UYH7
688
79624
I451
A
R
E
L
K
E
H
I
F
F
K
G
I
D
W
Rat
Rattus norvegicus
P26819
688
79869
I451
A
R
E
L
K
E
H
I
F
F
K
G
I
D
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519341
320
35761
D109
L
D
L
M
N
G
G
D
L
H
Y
H
L
S
Q
Chicken
Gallus gallus
XP_415195
616
71509
V405
L
I
P
P
R
G
E
V
N
A
A
D
A
F
D
Frog
Xenopus laevis
Q7ZX15
486
56292
N275
L
E
Y
L
H
S
R
N
V
V
Y
R
D
I
K
Zebra Danio
Brachydanio rerio
NP_001128197
688
79486
V451
A
S
E
V
K
E
H
V
F
F
K
G
I
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32865
700
80548
N452
A
D
E
V
K
M
H
N
F
F
C
G
I
D
W
Honey Bee
Apis mellifera
XP_396647
690
79440
P455
A
D
E
L
K
E
H
P
F
F
S
G
I
D
W
Nematode Worm
Caenorhab. elegans
Q09639
707
80960
H452
G
P
T
E
V
K
E
H
P
F
F
K
D
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81
95.3
91.8
N.A.
91.2
91.1
N.A.
36.3
84.1
23.8
90.5
N.A.
65.2
67.5
64.6
N.A.
Protein Similarity:
100
90.1
96
93.5
N.A.
96
96.3
N.A.
39.5
86.1
38.6
95.3
N.A.
77.5
79.1
78.5
N.A.
P-Site Identity:
100
60
100
80
N.A.
66.6
66.6
N.A.
0
0
0
73.3
N.A.
60
60
6.6
N.A.
P-Site Similarity:
100
80
100
93.3
N.A.
93.3
93.3
N.A.
13.3
6.6
20
86.6
N.A.
80
80
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
24
0
0
0
0
0
8
0
0
0
8
16
70
16
% D
% Glu:
0
8
70
8
0
62
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
70
77
8
0
0
8
0
% F
% Gly:
8
0
0
0
0
16
8
0
0
0
0
62
0
0
0
% G
% His:
0
0
0
0
8
0
62
8
0
8
0
8
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
24
0
0
0
0
47
8
0
% I
% Lys:
0
0
0
0
70
8
0
0
0
0
47
8
0
0
8
% K
% Leu:
24
0
8
31
0
0
0
0
8
0
0
0
16
0
0
% L
% Met:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
16
8
0
0
0
0
0
0
% N
% Pro:
0
8
8
8
0
0
0
16
8
0
0
0
0
0
0
% P
% Gln:
0
31
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
16
0
0
8
0
8
0
0
0
8
8
0
0
0
% R
% Ser:
16
8
0
0
0
8
8
16
0
0
8
8
0
8
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
47
8
0
0
16
8
8
0
0
16
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _