Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FUS All Species: 10.3
Human Site: S87 Identified Species: 28.33
UniProt: P35637 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35637 NP_004951.1 526 53426 S87 G Y G S S Q S S Q S S Y G Q Q
Chimpanzee Pan troglodytes XP_001158561 529 53899 S92 G Y G S S Q S S Q S S Y G Q Q
Rhesus Macaque Macaca mulatta XP_001112628 503 51743 Q87 Y G S S Q S S Q S S Y G Q Q S
Dog Lupus familis XP_860831 650 68230 Y98 Q G Y G A G A Y D T T T A M V
Cat Felis silvestris
Mouse Mus musculus P56959 518 52655 S88 G Y G S S Q S S Q S S Y G Q Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517600 561 57424 Q127 S G G Y G S S Q G S Q S S Y G
Chicken Gallus gallus
Frog Xenopus laevis P51992 385 39419
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27294 399 38820
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 92.5 45.3 N.A. 95 N.A. N.A. 85.1 N.A. 20.7 N.A. N.A. 23.9 N.A. 21.1 N.A.
Protein Similarity: 100 97.1 93.1 54.3 N.A. 95.4 N.A. N.A. 87.1 N.A. 31.5 N.A. N.A. 32.7 N.A. 31.5 N.A.
P-Site Identity: 100 100 26.6 0 N.A. 100 N.A. N.A. 20 N.A. 0 N.A. N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 26.6 N.A. 100 N.A. N.A. 20 N.A. 0 N.A. N.A. 0 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 12 0 12 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 34 34 45 12 12 12 0 0 12 0 0 12 34 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 12 34 0 23 34 0 12 0 12 45 34 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 0 12 45 34 23 56 34 12 56 34 12 12 0 12 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 12 12 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 34 12 12 0 0 0 12 0 0 12 34 0 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _