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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP214 All Species: 2.73
Human Site: S1181 Identified Species: 6.67
UniProt: P35658 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35658 NP_005076.3 2090 213620 S1181 P S G P T P A S G Q L S S G D
Chimpanzee Pan troglodytes XP_001166820 2121 216999 L1213 Q G S L I N S L K P S G P T P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850680 1239 128658 V330 V L W I G T Y V F T I V Y A A
Cat Felis silvestris
Mouse Mus musculus Q80U93 2085 212960 N1176 A K Q G S L I N S F K P S G P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506900 1777 179054 G869 P G P A G A S G I V I S G H I
Chicken Gallus gallus XP_425333 1458 152874 S550 N L K P S A E S S P G L P H S
Frog Xenopus laevis NP_001079666 2037 208914 N1128 V N V K E L K N N G P G P T I
Zebra Danio Brachydanio rerio XP_002662271 1013 102782 T105 K D S D P V M T G I L E E I G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1X4 1711 175157 K803 A A L L D Q E K S R T R T N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794482 3338 354012 T2426 A R P L T S Q T A P R P A A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.6 N.A. 51.8 N.A. 77.8 N.A. N.A. 53.7 51.9 49.9 26.8 N.A. 25.6 N.A. N.A. 20.6
Protein Similarity: 100 97.7 N.A. 53.6 N.A. 84.6 N.A. N.A. 62.6 58.9 65.7 34.5 N.A. 41.4 N.A. N.A. 33.3
P-Site Identity: 100 0 N.A. 0 N.A. 13.3 N.A. N.A. 13.3 13.3 0 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 6.6 N.A. 6.6 N.A. 26.6 N.A. N.A. 26.6 20 13.3 20 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 30 10 0 10 0 20 10 0 10 0 0 0 10 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 10 % D
% Glu: 0 0 0 0 10 0 20 0 0 0 0 10 10 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % F
% Gly: 0 20 10 10 20 0 0 10 20 10 10 20 10 20 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % H
% Ile: 0 0 0 10 10 0 10 0 10 10 20 0 0 10 20 % I
% Lys: 10 10 10 10 0 0 10 10 10 0 10 0 0 0 0 % K
% Leu: 0 20 10 30 0 20 0 10 0 0 20 10 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 10 0 20 10 0 0 0 0 10 0 % N
% Pro: 20 0 20 20 10 10 0 0 0 30 10 20 30 0 20 % P
% Gln: 10 0 10 0 0 10 10 0 0 10 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 10 10 0 0 0 % R
% Ser: 0 10 20 0 20 10 20 20 30 0 10 20 20 0 20 % S
% Thr: 0 0 0 0 20 10 0 20 0 10 10 0 10 20 0 % T
% Val: 20 0 10 0 0 10 0 10 0 10 0 10 0 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _