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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
16.67
Human Site:
S159
Identified Species:
33.33
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S159
F
R
N
A
M
L
K
S
I
C
E
V
L
D
L
Chimpanzee
Pan troglodytes
XP_518259
308
35142
C94
N
A
M
L
K
S
I
C
E
V
L
D
L
E
R
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S159
F
R
N
A
M
L
K
S
I
C
E
V
L
D
L
Dog
Lupus familis
XP_853159
361
41239
C147
N
A
M
L
K
S
I
C
E
V
L
D
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S163
F
R
N
A
M
L
K
S
I
C
E
V
L
D
L
Rat
Rattus norvegicus
Q6AXS3
378
42874
S161
Y
R
N
A
M
L
K
S
I
C
E
V
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
L154
K
K
F
R
N
A
M
L
K
S
I
C
E
V
L
Frog
Xenopus laevis
NP_001167471
391
44331
N168
W
K
K
I
D
L
K
N
T
C
G
V
L
D
L
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
D226
S
D
D
D
D
D
D
D
D
D
D
D
G
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
S292
V
D
N
K
G
L
R
S
I
C
E
I
L
T
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
K221
L
D
K
C
V
K
E
K
L
M
D
F
C
D
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
6.6
100
6.6
N.A.
100
93.3
N.A.
N.A.
6.6
46.6
6.6
N.A.
53.3
N.A.
N.A.
0
P-Site Similarity:
100
13.3
100
13.3
N.A.
100
100
N.A.
N.A.
13.3
66.6
20
N.A.
66.6
N.A.
N.A.
0
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
34
0
9
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
17
0
50
0
9
9
0
0
% C
% Asp:
0
25
9
9
17
9
9
9
9
9
17
25
0
59
0
% D
% Glu:
0
0
0
0
0
0
9
0
17
0
42
0
9
17
9
% E
% Phe:
25
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
0
0
0
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
17
0
42
0
9
9
0
0
0
% I
% Lys:
9
17
17
9
17
9
42
9
9
0
0
0
0
0
0
% K
% Leu:
9
0
0
17
0
50
0
9
9
0
17
0
67
0
59
% L
% Met:
0
0
17
0
34
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
17
0
42
0
9
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
34
0
9
0
0
9
0
0
0
0
0
0
0
17
% R
% Ser:
9
0
0
0
0
17
0
42
0
9
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% T
% Val:
9
0
0
0
9
0
0
0
0
17
0
42
0
9
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _