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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEK All Species: 4.24
Human Site: S196 Identified Species: 8.48
UniProt: P35659 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35659 NP_001128181.1 375 42674 S196 S G K P L P K S K K T C S K G
Chimpanzee Pan troglodytes XP_518259 308 35142 K130 G K P L P K S K K T C S K G S
Rhesus Macaque Macaca mulatta XP_001101463 375 42582 S196 S G K P L P K S K K T S S K G
Dog Lupus familis XP_853159 361 41239 K183 G K P L P K S K K S S S K G N
Cat Felis silvestris
Mouse Mus musculus Q7TNV0 380 43140 K201 G K P L P K S K K S S S K G S
Rat Rattus norvegicus Q6AXS3 378 42874 K199 G K P L P K S K K S S S K G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012578 369 42145 L190 P K S S G K P L P K S K K T P
Frog Xenopus laevis NP_001167471 391 44331 A212 I K G K S P K A S K K D R S S
Zebra Danio Brachydanio rerio NP_001038741 442 49931 E263 S E D K S D I E E E D E S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995861 612 65912 A423 G S D Y N P S A N S D S D G G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181560 201 22965 D23 Q K D E K D K D G D K E G E E
Poplar Tree Populus trichocarpa XP_002318149 574 63311 K363 K E Q T P S K K S K K S S K Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 98.9 89.8 N.A. 91.3 92 N.A. N.A. 81.5 62.6 41.1 N.A. 24.1 N.A. N.A. 22.6
Protein Similarity: 100 82.1 99.4 93 N.A. 95 96.5 N.A. N.A. 90.1 77.4 56.5 N.A. 37.7 N.A. N.A. 35.2
P-Site Identity: 100 6.6 93.3 6.6 N.A. 6.6 6.6 N.A. N.A. 6.6 20 13.3 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 6.6 93.3 13.3 N.A. 13.3 13.3 N.A. N.A. 13.3 26.6 26.6 N.A. 20 N.A. N.A. 13.3
Percent
Protein Identity: 28.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % C
% Asp: 0 0 25 0 0 17 0 9 0 9 17 9 9 0 9 % D
% Glu: 0 17 0 9 0 0 0 9 9 9 0 17 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 42 17 9 0 9 0 0 0 9 0 0 0 9 42 25 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 17 17 9 42 42 42 50 42 25 9 42 25 0 % K
% Leu: 0 0 0 34 17 0 0 9 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 9 % N
% Pro: 9 0 34 17 42 34 9 0 9 0 0 0 0 0 9 % P
% Gln: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 25 9 9 9 17 9 42 17 17 34 34 59 34 17 34 % S
% Thr: 0 0 0 9 0 0 0 0 0 9 17 0 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _