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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEK All Species: 16.67
Human Site: S230 Identified Species: 33.33
UniProt: P35659 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35659 NP_001128181.1 375 42674 S230 P E I L S D E S S S D E D E K
Chimpanzee Pan troglodytes XP_518259 308 35142 S164 E I L S D E S S S D E D E K K
Rhesus Macaque Macaca mulatta XP_001101463 375 42582 S230 P E I L S D E S S S D E D E K
Dog Lupus familis XP_853159 361 41239 S217 E I L S D E S S S D E D E K K
Cat Felis silvestris
Mouse Mus musculus Q7TNV0 380 43140 S235 E I L S D E S S S D E D E K K
Rat Rattus norvegicus Q6AXS3 378 42874 S233 E I L S D E S S S D E D E K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012578 369 42145 S224 T K C P E I L S D E S S S E E
Frog Xenopus laevis NP_001167471 391 44331 K246 S S S E D E K K D K E E S S E
Zebra Danio Brachydanio rerio NP_001038741 442 49931 G297 P Q K K S S T G K S T K K S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995861 612 65912 R457 R P A R K S R R R N S D S E E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181560 201 22965 G57 A P V Q I M T G K R D R K K V
Poplar Tree Populus trichocarpa XP_002318149 574 63311 K397 K P V K G L E K S T K K S S D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 98.9 89.8 N.A. 91.3 92 N.A. N.A. 81.5 62.6 41.1 N.A. 24.1 N.A. N.A. 22.6
Protein Similarity: 100 82.1 99.4 93 N.A. 95 96.5 N.A. N.A. 90.1 77.4 56.5 N.A. 37.7 N.A. N.A. 35.2
P-Site Identity: 100 20 100 20 N.A. 20 20 N.A. N.A. 13.3 6.6 20 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 60 100 60 N.A. 60 60 N.A. N.A. 26.6 33.3 33.3 N.A. 26.6 N.A. N.A. 20
Percent
Protein Identity: 28.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 42 17 0 0 17 34 25 42 17 0 17 % D
% Glu: 34 17 0 9 9 42 25 0 0 9 42 25 34 34 25 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 17 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 34 17 0 9 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 9 9 17 9 0 9 17 17 9 9 17 17 42 50 % K
% Leu: 0 0 34 17 0 9 9 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % N
% Pro: 25 25 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 9 0 0 9 9 9 9 0 9 0 0 0 % R
% Ser: 9 9 9 34 25 17 34 59 59 25 17 9 34 25 0 % S
% Thr: 9 0 0 0 0 0 17 0 0 9 9 0 0 0 0 % T
% Val: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _