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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
16.97
Human Site:
S231
Identified Species:
33.94
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S231
E
I
L
S
D
E
S
S
S
D
E
D
E
K
K
Chimpanzee
Pan troglodytes
XP_518259
308
35142
S165
I
L
S
D
E
S
S
S
D
E
D
E
K
K
N
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S231
E
I
L
S
D
E
S
S
S
D
E
D
E
K
K
Dog
Lupus familis
XP_853159
361
41239
S218
I
L
S
D
E
S
S
S
D
E
D
E
K
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S236
I
L
S
D
E
S
S
S
D
E
D
E
K
K
N
Rat
Rattus norvegicus
Q6AXS3
378
42874
S234
I
L
S
D
E
S
S
S
D
E
D
E
K
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
D225
K
C
P
E
I
L
S
D
E
S
S
S
E
E
D
Frog
Xenopus laevis
NP_001167471
391
44331
D247
S
S
E
D
E
K
K
D
K
E
E
S
S
E
E
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
K298
Q
K
K
S
S
T
G
K
S
T
K
K
S
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
R458
P
A
R
K
S
R
R
R
N
S
D
S
E
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
K58
P
V
Q
I
M
T
G
K
R
D
R
K
K
V
E
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
S398
P
V
K
G
L
E
K
S
T
K
K
S
S
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
20
100
20
N.A.
20
20
N.A.
N.A.
13.3
6.6
20
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
60
100
60
N.A.
60
60
N.A.
N.A.
26.6
40
33.3
N.A.
33.3
N.A.
N.A.
26.6
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
42
17
0
0
17
34
25
42
17
0
17
9
% D
% Glu:
17
0
9
9
42
25
0
0
9
42
25
34
34
25
25
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
17
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
17
9
0
9
17
17
9
9
17
17
42
50
25
% K
% Leu:
0
34
17
0
9
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
34
% N
% Pro:
25
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
9
9
9
0
9
0
0
0
0
% R
% Ser:
9
9
34
25
17
34
59
59
25
17
9
34
25
0
9
% S
% Thr:
0
0
0
0
0
17
0
0
9
9
0
0
0
0
0
% T
% Val:
0
17
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _