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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DEK All Species: 13.94
Human Site: S271 Identified Species: 27.88
UniProt: P35659 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35659 NP_001128181.1 375 42674 S271 K P K Q K A T S K S K K S V K
Chimpanzee Pan troglodytes XP_518259 308 35142 K205 P K Q K A T S K S K K S V K S
Rhesus Macaque Macaca mulatta XP_001101463 375 42582 S271 K P K Q K A T S K S K K S V K
Dog Lupus familis XP_853159 361 41239 K258 P K Q K A T S K S K K T V K S
Cat Felis silvestris
Mouse Mus musculus Q7TNV0 380 43140 A276 K A K Q K A T A K S K K S V K
Rat Rattus norvegicus Q6AXS3 378 42874 T274 K A K Q K A T T K S K K S V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012578 369 42145 S265 E K S K K V T S K P K K T V K
Frog Xenopus laevis NP_001167471 391 44331 K287 P K G K K A A K S A N V K K A
Zebra Danio Brachydanio rerio NP_001038741 442 49931 K338 T K K K P A A K R K A P A K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_995861 612 65912 G498 P A A P A S A G R R G R G R G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001181560 201 22965 H98 G D I P I V A H F L E K T K S
Poplar Tree Populus trichocarpa XP_002318149 574 63311 S438 K Q K V E K E S P K D R S A S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.1 98.9 89.8 N.A. 91.3 92 N.A. N.A. 81.5 62.6 41.1 N.A. 24.1 N.A. N.A. 22.6
Protein Similarity: 100 82.1 99.4 93 N.A. 95 96.5 N.A. N.A. 90.1 77.4 56.5 N.A. 37.7 N.A. N.A. 35.2
P-Site Identity: 100 6.6 100 6.6 N.A. 86.6 86.6 N.A. N.A. 53.3 13.3 13.3 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 26.6 N.A. 93.3 93.3 N.A. N.A. 73.3 26.6 33.3 N.A. 20 N.A. N.A. 20
Percent
Protein Identity: 28.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 41.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 9 0 25 50 34 9 0 9 9 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % D
% Glu: 9 0 0 0 9 0 9 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 0 0 0 9 0 0 9 0 9 0 9 % G
% His: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 42 42 50 42 50 9 0 34 42 34 59 50 9 42 42 % K
% Leu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 34 17 0 17 9 0 0 0 9 9 0 9 0 0 9 % P
% Gln: 0 9 17 34 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 17 9 0 17 0 9 0 % R
% Ser: 0 0 9 0 0 9 17 34 25 34 0 9 42 0 34 % S
% Thr: 9 0 0 0 0 17 42 9 0 0 0 9 17 0 0 % T
% Val: 0 0 0 9 0 17 0 0 0 0 0 9 17 42 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _