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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
13.64
Human Site:
S273
Identified Species:
27.27
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.45
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S273
K
Q
K
A
T
S
K
S
K
K
S
V
K
S
A
Chimpanzee
Pan troglodytes
XP_518259
308
35142
K207
Q
K
A
T
S
K
S
K
K
S
V
K
S
A
N
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S273
K
Q
K
A
T
S
K
S
K
K
S
V
K
S
A
Dog
Lupus familis
XP_853159
361
41239
K260
Q
K
A
T
S
K
S
K
K
T
V
K
S
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S278
K
Q
K
A
T
A
K
S
K
K
S
V
K
S
A
Rat
Rattus norvegicus
Q6AXS3
378
42874
S276
K
Q
K
A
T
T
K
S
K
K
S
V
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
P267
S
K
K
V
T
S
K
P
K
K
T
V
K
G
A
Frog
Xenopus laevis
NP_001167471
391
44331
A289
G
K
K
A
A
K
S
A
N
V
K
K
A
D
S
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
K340
K
K
P
A
A
K
R
K
A
P
A
K
P
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
R500
A
P
A
S
A
G
R
R
G
R
G
R
G
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
L100
I
P
I
V
A
H
F
L
E
K
T
K
S
Q
D
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
K440
K
V
E
K
E
S
P
K
D
R
S
A
S
S
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
6.6
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
60
13.3
13.3
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
100
33.3
N.A.
100
100
N.A.
N.A.
73.3
33.3
33.3
N.A.
33.3
N.A.
N.A.
20
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
50
34
9
0
9
9
0
9
9
9
25
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
9
% D
% Glu:
0
0
9
0
9
0
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
0
9
0
9
0
9
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
42
50
9
0
34
42
34
59
50
9
42
42
0
9
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
17
% N
% Pro:
0
17
9
0
0
0
9
9
0
9
0
0
9
0
9
% P
% Gln:
17
34
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
17
9
0
17
0
9
0
0
0
% R
% Ser:
9
0
0
9
17
34
25
34
0
9
42
0
34
42
9
% S
% Thr:
0
0
0
17
42
9
0
0
0
9
17
0
0
0
0
% T
% Val:
0
9
0
17
0
0
0
0
0
9
17
42
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _