KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
25.15
Human Site:
S303
Identified Species:
50.3
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S303
S
S
K
K
E
S
E
S
E
D
S
S
D
D
E
Chimpanzee
Pan troglodytes
XP_518259
308
35142
E237
S
K
K
E
S
E
S
E
D
S
S
D
D
E
P
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S303
S
S
K
K
E
S
E
S
E
D
S
S
D
D
E
Dog
Lupus familis
XP_853159
361
41239
E290
S
K
K
E
S
E
S
E
D
S
S
D
D
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S308
S
S
K
K
E
S
E
S
E
D
S
S
D
D
E
Rat
Rattus norvegicus
Q6AXS3
378
42874
S306
S
S
K
K
E
S
G
S
E
D
S
S
D
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
S297
S
S
R
K
E
S
E
S
E
D
S
S
D
N
E
Frog
Xenopus laevis
NP_001167471
391
44331
S319
A
V
P
S
E
S
E
S
D
D
S
S
D
D
E
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
S370
A
S
K
R
K
D
E
S
E
S
S
D
D
D
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
V530
E
D
E
E
E
E
D
V
S
D
F
A
S
D
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
I130
P
R
E
N
K
R
N
I
R
Q
F
S
G
F
E
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
F470
A
S
A
K
D
Q
A
F
A
V
K
K
G
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
26.6
100
26.6
N.A.
100
93.3
N.A.
N.A.
86.6
66.6
53.3
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
46.6
100
46.6
N.A.
100
93.3
N.A.
N.A.
100
80
80
N.A.
53.3
N.A.
N.A.
26.6
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
9
0
0
0
9
0
9
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
9
9
0
25
59
0
25
75
59
0
% D
% Glu:
9
0
17
25
59
25
50
17
50
0
0
0
0
17
59
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
17
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
17
59
50
17
0
0
0
0
0
9
9
0
9
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% N
% Pro:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
9
0
0
0
9
0
0
0
0
17
% Q
% Arg:
0
9
9
9
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
59
59
0
9
17
50
17
59
9
25
75
59
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
9
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _