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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
29.39
Human Site:
S306
Identified Species:
58.79
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S306
K
E
S
E
S
E
D
S
S
D
D
E
P
L
I
Chimpanzee
Pan troglodytes
XP_518259
308
35142
S240
E
S
E
S
E
D
S
S
D
D
E
P
L
I
K
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S306
K
E
S
E
S
E
D
S
S
D
D
E
P
L
I
Dog
Lupus familis
XP_853159
361
41239
S293
E
S
E
S
E
D
S
S
D
D
E
P
L
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S311
K
E
S
E
S
E
D
S
S
D
D
E
P
L
I
Rat
Rattus norvegicus
Q6AXS3
378
42874
S309
K
E
S
G
S
E
D
S
S
D
D
E
P
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
S300
K
E
S
E
S
E
D
S
S
D
N
E
P
L
I
Frog
Xenopus laevis
NP_001167471
391
44331
S322
S
E
S
E
S
D
D
S
S
D
D
E
P
L
I
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
S373
R
K
D
E
S
E
S
S
D
D
D
Q
P
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
F533
E
E
E
D
V
S
D
F
A
S
D
Q
S
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
F133
N
K
R
N
I
R
Q
F
S
G
F
E
F
S
K
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
K473
K
D
Q
A
F
A
V
K
K
G
K
A
K
S
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
13.3
100
13.3
N.A.
100
93.3
N.A.
N.A.
93.3
86.6
60
N.A.
20
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
40
N.A.
100
93.3
N.A.
N.A.
100
93.3
80
N.A.
46.6
N.A.
N.A.
20
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
0
9
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
0
25
59
0
25
75
59
0
0
0
0
% D
% Glu:
25
59
25
50
17
50
0
0
0
0
17
59
0
9
9
% E
% Phe:
0
0
0
0
9
0
0
17
0
0
9
0
9
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
0
0
17
59
% I
% Lys:
50
17
0
0
0
0
0
9
9
0
9
0
9
0
25
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
17
59
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
17
59
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
17
0
0
0
% Q
% Arg:
9
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
17
50
17
59
9
25
75
59
9
0
0
9
17
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _