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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEK
All Species:
20
Human Site:
S99
Identified Species:
40
UniProt:
P35659
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35659
NP_001128181.1
375
42674
S99
E
R
I
H
F
F
L
S
K
K
K
T
D
E
L
Chimpanzee
Pan troglodytes
XP_518259
308
35142
T36
F
F
L
S
K
K
K
T
D
E
L
R
N
L
H
Rhesus Macaque
Macaca mulatta
XP_001101463
375
42582
S99
E
R
I
H
F
F
L
S
K
K
K
T
D
E
L
Dog
Lupus familis
XP_853159
361
41239
T89
F
F
L
S
K
K
K
T
D
E
L
R
N
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNV0
380
43140
S103
E
R
I
H
F
F
L
S
K
K
K
P
D
E
L
Rat
Rattus norvegicus
Q6AXS3
378
42874
S101
E
R
I
H
F
F
L
S
K
K
K
T
D
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012578
369
42145
S96
E
R
I
Q
F
F
L
S
K
K
K
T
D
E
L
Frog
Xenopus laevis
NP_001167471
391
44331
K108
E
R
V
Q
Y
F
L
K
K
K
K
C
E
E
L
Zebra Danio
Brachydanio rerio
NP_001038741
442
49931
M165
V
V
L
S
E
R
I
M
K
F
L
A
Q
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_995861
612
65912
N232
D
R
I
N
E
N
I
N
K
T
R
V
D
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181560
201
22965
Poplar Tree
Populus trichocarpa
XP_002318149
574
63311
K163
N
V
A
F
K
L
S
K
R
K
A
D
D
N
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
98.9
89.8
N.A.
91.3
92
N.A.
N.A.
81.5
62.6
41.1
N.A.
24.1
N.A.
N.A.
22.6
Protein Similarity:
100
82.1
99.4
93
N.A.
95
96.5
N.A.
N.A.
90.1
77.4
56.5
N.A.
37.7
N.A.
N.A.
35.2
P-Site Identity:
100
0
100
0
N.A.
93.3
100
N.A.
N.A.
93.3
60
6.6
N.A.
33.3
N.A.
N.A.
0
P-Site Similarity:
100
26.6
100
26.6
N.A.
93.3
100
N.A.
N.A.
93.3
80
20
N.A.
66.6
N.A.
N.A.
0
Percent
Protein Identity:
28.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
17
0
0
9
59
0
0
% D
% Glu:
50
0
0
0
17
0
0
0
0
17
0
0
9
50
0
% E
% Phe:
17
17
0
9
42
50
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% G
% His:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
50
0
0
0
17
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
25
17
17
17
67
59
50
0
0
0
0
% K
% Leu:
0
0
25
0
0
9
50
0
0
0
25
0
0
17
67
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
9
0
9
0
0
0
0
17
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
59
0
0
0
9
0
0
9
0
9
17
0
0
0
% R
% Ser:
0
0
0
25
0
0
9
42
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
0
9
0
34
0
0
9
% T
% Val:
9
17
9
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _