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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7B
All Species:
4.24
Human Site:
S1116
Identified Species:
8.48
UniProt:
P35670
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35670
NP_000044.2
1465
157263
S1116
V
E
G
I
L
A
H
S
E
R
P
L
S
A
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
N1025
N
R
E
W
L
R
R
N
G
L
T
I
S
S
D
Dog
Lupus familis
XP_860306
1504
164598
D1137
I
E
G
L
L
H
K
D
N
W
K
I
E
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64446
1462
157279
S1118
V
E
G
I
L
A
R
S
D
L
T
A
H
P
V
Rat
Rattus norvegicus
Q64535
1451
155972
R1109
V
E
S
I
L
A
H
R
G
P
T
A
H
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S1243
I
E
A
L
L
T
K
S
N
W
K
I
E
E
K
Chicken
Gallus gallus
XP_417073
1516
163625
A1176
V
D
A
V
L
G
T
A
E
E
G
V
D
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
E1118
T
E
N
L
L
K
R
E
D
S
D
S
E
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
A949
E
E
R
K
G
H
T
A
V
L
C
A
L
N
G
Honey Bee
Apis mellifera
XP_395837
1274
139224
K969
I
P
Q
E
V
E
L
K
M
V
A
E
E
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
L690
V
L
R
E
F
Y
E
L
V
A
A
T
E
V
N
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
V699
V
V
L
E
S
E
Y
V
L
G
K
G
I
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88
56.5
N.A.
82.8
82.3
N.A.
49.7
68
N.A.
56.3
N.A.
40.8
42.5
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
72.5
N.A.
89.9
88.8
N.A.
65.1
80.9
N.A.
71.5
N.A.
57.5
59.3
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
20
N.A.
46.6
40
N.A.
20
20
N.A.
13.3
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
33.3
40
N.A.
53.3
40
N.A.
40
46.6
N.A.
26.6
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
26.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
25
0
17
0
9
17
25
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
17
0
9
0
9
0
9
% D
% Glu:
9
59
9
25
0
17
9
9
17
9
0
9
42
34
9
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
25
0
9
9
0
0
17
9
9
9
0
0
9
% G
% His:
0
0
0
0
0
17
17
0
0
0
0
0
17
0
0
% H
% Ile:
25
0
0
25
0
0
0
0
0
0
0
25
9
0
9
% I
% Lys:
0
0
0
9
0
9
17
9
0
0
25
0
0
0
9
% K
% Leu:
0
9
9
25
67
0
9
9
9
25
0
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
9
0
0
0
0
9
17
0
0
0
0
17
25
% N
% Pro:
0
9
0
0
0
0
0
0
0
9
9
0
0
17
9
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
17
0
0
9
25
9
0
9
0
0
0
0
0
% R
% Ser:
0
0
9
0
9
0
0
25
0
9
0
9
17
9
9
% S
% Thr:
9
0
0
0
0
9
17
0
0
0
25
9
0
0
0
% T
% Val:
50
9
0
9
9
0
0
9
17
9
0
9
0
17
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _